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良性前列腺增生与老年男性跌倒风险:基于老年疾病人群研究的见解

Benign Prostatic Hyperplasia and the Risk of Falls in Older Men: Insights From a Population-Based Study on Geriatric Morbid Conditions.

作者信息

Kim Sung Jin, Lee Donghyun, Park Sung Gon, Pak Sahyun, Lee Young Goo, Cho Sung Tae

机构信息

Department of Urology, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.

Department of Urology, Yeongwol Medical Center, Yeongwol, Korea.

出版信息

Int Neurourol J. 2024 Mar;28(1):44-51. doi: 10.5213/inj.2448064.032. Epub 2024 Mar 31.

Abstract

PURPOSE

The purpose of this study was to explore the association between benign prostatic hyperplasia (BPH) and the incidence of falls from the perspective of geriatric morbid conditions.

METHODS

Data were sourced from the triennial National Survey of Older Koreans conducted by the Ministry of Health and Welfare (2017-2020). In total, 8,135 male participants aged 65 and older were included, and information was gathered through questionnaires and physical measurements. Logistic regression analysis was utilized to determine the impact of BPH on the risk of falls, and subgroup analyses were conducted to examine the influence of BPH on specific types of falls.

RESULTS

Of the participants, 15.2% (1,238 of 8,135) reported that their BPH treatment exceeded 3 months, and 8.0% (648 of 8,135) reported experiencing falls, with 61.4% (398/648) of these falls resulting in injuries. A significant association was identified between BPH and both falls (odds ratio [OR], 1.798; 95% confidence interval [CI], 1.479-2.185) and falls with injuries (OR, 2.133; 95% CI, 1.689-2.694). A subgroup analysis indicated a correlation between BPH and falls in groups having one (OR, 1.912; 95% CI, 1.356-2.694) and 2 or more conditions (OR, 1.856; 95% CI, 1.455-2.367) involving visual and auditory impairments, cognitive decline, depression, lower motor weakness, and limitations in daily activities.

CONCLUSION

The findings indicate that BPH contributes to the incidence of falls among older men, particularly those with comorbid conditions. Considering the heightened fall risk among elderly individuals suffering from multiple morbidities, particularly those with BPH, targeted interventions are essential for mitigating the risk of falls in this vulnerable group.

摘要

目的

本研究旨在从老年疾病的角度探讨良性前列腺增生(BPH)与跌倒发生率之间的关联。

方法

数据来源于韩国卫生与福利部进行的每三年一次的全国老年人调查(2017 - 2020年)。总共纳入了8135名65岁及以上的男性参与者,通过问卷调查和身体测量收集信息。采用逻辑回归分析来确定BPH对跌倒风险的影响,并进行亚组分析以检验BPH对特定类型跌倒的影响。

结果

在参与者中,15.2%(8135人中的1238人)报告其BPH治疗超过3个月,8.0%(8135人中的648人)报告有跌倒经历,其中61.4%(398/648)的跌倒导致受伤。在BPH与跌倒(优势比[OR],1.798;95%置信区间[CI],1.479 - 2.185)以及跌倒致伤(OR,2.133;95%CI,1.689 - 2.694)之间均发现了显著关联。亚组分析表明,在患有一种(OR,1.912;95%CI,1.356 - 2.694)以及两种或更多种涉及视力和听力障碍、认知衰退、抑郁、下肢运动无力和日常生活受限等情况的人群中,BPH与跌倒之间存在相关性。

结论

研究结果表明,BPH会导致老年男性跌倒发生率上升,尤其是那些患有合并症的男性。鉴于患有多种疾病的老年人,特别是患有BPH的老年人跌倒风险更高,针对性干预对于降低这一弱势群体的跌倒风险至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a37b/10990761/3ca1d761bf1a/inj-2448064-032f1.jpg

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