Rousset A, Tytgat F, Minck R
J Gynecol Obstet Biol Reprod (Paris). 1979 Apr-May;8(3):219-21.
A bacteriological study of 10,962 vaginal swabs has made it possible to work out the percentage of women who are carriers of Group B streptococci in their vaginas. The count varies between 9.43 and 17.25 per cent according to the different populations that were studied. Serotyping of the strains of 1,030 vaginal specimens was carried out and it was found that serotypes II and III predominated. We have been able to study 27 strains responsible for infection in the early neonatal period such as septicaemia or meningitis at the same time as we were studying the vaginal flora. The distribution of the serotypes illustrates a predominance of types 1c and III in 70 per cent of cases. Contamination between the mother and the child is obvious but in 95 per cent of cases the strain isolated in the infected child was of the same serotype as that which was isolated in the mother. Group B streptococci are still very sensitive to antibiotics and particularly to the penicillins. It does seem to us to be unrealistic to treat with antibiotics prophylactically in pregnancy. On the other hand careful attention to the newborn and careful bacteriological study of multiple specimens taken from the skin and the orifices gives easy screening for the germ and the possibility of treating infants that are grossly contaminated.
对10962份阴道拭子进行的细菌学研究,使我们能够计算出阴道内携带B族链球菌的女性比例。根据所研究的不同人群,这一比例在9.43%至17.25%之间变化。对1030份阴道标本的菌株进行了血清分型,发现血清型II和III占主导地位。在研究阴道菌群的同时,我们能够研究27株导致新生儿早期感染(如败血症或脑膜炎)的菌株。血清型的分布表明,70%的病例中1c型和III型占主导地位。母婴之间的感染很明显,但在95%的病例中,感染儿童分离出的菌株与母亲分离出的菌株血清型相同。B族链球菌仍然对抗生素非常敏感,尤其是对青霉素。在我们看来,孕期预防性使用抗生素是不现实的。另一方面,对新生儿进行仔细观察,并对从皮肤和孔窍采集的多个标本进行仔细的细菌学研究,便于筛查病菌,并有可能治疗严重感染的婴儿。