Department of Anesthesiology, The Research Units of West China (2018RU012), West China Hospital, Sichuan University, Chinese Academy of Medical Sciences, Chengdu, 610041, China.
West China Xiamen Hospital of Sichuan University, 361000, Xiamen, China.
Trials. 2024 Apr 3;25(1):231. doi: 10.1186/s13063-024-08071-3.
Breast cancer is the most prevalent cancer among women globally, and surgical procedures continue to be the primary treatment. However, over 50% of patients experience preoperative anxiety due to the unknown and fear associated with surgery. Although drug therapy is commonly used to address this anxiety, its side effects have led to a heated debate regarding its effectiveness. Consequently, non-pharmacological therapies, such as preoperative education, have emerged as an alternative approach to alleviate anxiety. WeChat, a widely popular social media platform, offers a public platform that can potentially be utilized for effective preoperative education. This study aims to evaluate the use of WeChat public platform as a tool for preoperative education in patients undergoing breast surgery.
This is a prospective, randomized, and controlled trial will involve 392 adult women scheduled for breast cancer resection. Participants will be randomly assigned to either the WeChat education group or the regular group. In addition to regular preoperative visits, the WeChat education group will also watch science videos through the WeChat public platform. The regular group will only receive education from ward nurses during preoperative visits. The primary outcome measure will be the incidence of preoperative anxiety, defined by scores of the State Anxiety Inventory (SAI) exceeding 40 points. Secondary outcome measures include the incidence of severe anxiety (SAI > 44) on the day before surgery, incidence of anxiety 72 h after surgery, incidence of severe anxiety 72 h after surgery, NRS scores for pain at rest and during activity 24, 48, and 72 h after surgery, incidence of nausea and vomiting within 24 h after surgery, subjective sleep score at 1 week postoperatively, quality of life QoR-15 scores at 1 and 3 months postoperatively, incidence of chronic pain at 3 months postoperatively, bowel function recovery, length of hospital stay, and hospitalization expenses.
This is the first clinical trial to investigate the use of WeChat public platform for delivering preoperative education on perioperative anxiety in breast cancer patients. By utilizing the renowned WeChat public platform, our study aims to improve patient outcomes by providing video education that explains the disease, surgery, and anesthesia in a more accessible manner, thereby reducing the incidence of perioperative anxiety. If our hypothesis is confirmed, this non-pharmacological approach can be universally acknowledged as a cost-effective and practical method in clinical care. Its application can also be extended to other medical fields beyond breast cancer.
ClinicalTrials.gov, NCT05291494. Registered on 29 December 2021.
乳腺癌是全球女性最常见的癌症，手术仍然是主要的治疗方法。然而，超过 50%的患者在术前会感到焦虑，这是由于对手术的未知和恐惧引起的。尽管药物治疗常用于治疗这种焦虑，但它的副作用引发了关于其有效性的激烈争论。因此，非药物治疗方法，如术前教育，已成为减轻焦虑的一种替代方法。微信是一个广受欢迎的社交媒体平台，它提供了一个公共平台，可能可以用于有效的术前教育。本研究旨在评估微信公众平台作为乳腺癌手术患者术前教育工具的应用。
这是一项前瞻性、随机、对照试验，将涉及 392 名成年女性乳腺癌切除术患者。参与者将被随机分配到微信教育组或常规组。除了常规术前访视外，微信教育组还将通过微信公众平台观看科学视频。常规组仅在术前访视时接受病房护士的教育。主要结局指标是术前焦虑的发生率，定义为状态焦虑量表（SAI）评分超过 40 分。次要结局指标包括手术前一天严重焦虑（SAI>44）的发生率、术后 72 小时焦虑的发生率、术后 72 小时严重焦虑的发生率、术后 24、48 和 72 小时静息和活动时的 NRS 疼痛评分、术后 24 小时内恶心和呕吐的发生率、术后 1 周的主观睡眠评分、术后 1 和 3 个月的生活质量 QoR-15 评分、术后 3 个月的慢性疼痛发生率、肠道功能恢复、住院时间和住院费用。
这是第一项研究微信公众平台在乳腺癌患者围手术期焦虑症术前教育中的应用的临床试验。通过利用著名的微信公众平台，我们的研究旨在通过提供更易于理解的疾病、手术和麻醉视频教育来改善患者的结局，从而降低围手术期焦虑的发生率。如果我们的假设得到证实，这种非药物治疗方法可以被普遍认为是一种具有成本效益和实用的临床护理方法。其应用也可以扩展到乳腺癌以外的其他医学领域。
ClinicalTrials.gov，NCT05291494。于 2021 年 12 月 29 日注册。
