University of California, San Francisco, San Francisco, California.
Icahn School of Medicine at Mount Sinai, New York, New York.
Arthritis Care Res (Hoboken). 2024 Aug;76(8):1109-1115. doi: 10.1002/acr.25341. Epub 2024 May 2.
To determine next steps for lay health worker (LHW) intervention research, specifically in patients with rheumatic musculoskeletal diseases (RMDs), there is a need to establish what strategies have been effective for chronic disease management thus far. The goal of this scoping review is to collate the literature of LHW interventions for adults with RMDs to inform next steps for LHW research.
A comprehensive literature search was performed in the following databases from inception to September 2021: Ovid Medline, Ovid Embase, CINAHL, PsycINFO, and The Cochrane Library. Studies retrieved were then screened for eligibility against predefined inclusion and exclusion criteria.
Twenty-two articles were eligible and included in this review. The most common RMDs studied, not mutually exclusive, were osteoarthritis (n = 13), rheumatoid arthritis (n = 9), and unspecified or other RMD (n = 14). Most studies had a homogenous patient population, enrolling White, non-Hispanic, or Latina women over the age of 60 (n = 13). Eight studies observed statistically significant results in the intervention arm compared with the control. Only one of these studies exhibited sustained treatment effects past one year.
There are not enough data to conclude if LHW interventions have a positive, null, or negative effect on patients with RMDs. Future LHW interventions should specify a priori hypotheses, be powered to detect statistical significance for primary outcomes, employ a theoretical framework, include an active control, describe training protocols for LHWs, and increase minority representation to establish the effectiveness of LHWs for patients with RMDs.
为了确定基层卫生工作者(LHW)干预研究的下一步措施,特别是在风湿性肌肉骨骼疾病(RMD)患者中,有必要确定迄今为止哪些策略对慢性病管理有效。本范围综述的目的是整理 LHW 干预成人 RMD 的文献,为 LHW 研究提供下一步的信息。
从成立到 2021 年 9 月,在以下数据库中进行了全面的文献检索:Ovid Medline、Ovid Embase、CINAHL、PsycINFO 和 The Cochrane Library。然后筛选检索到的研究,以符合预先设定的纳入和排除标准。
有 22 篇文章符合并包括在本次综述中。研究中最常见的 RMD(非互斥)为骨关节炎(n = 13)、类风湿关节炎(n = 9)和未特指或其他 RMD(n = 14)。大多数研究的患者人群具有同质性,招募白人、非西班牙裔或拉丁裔女性,年龄在 60 岁以上(n = 13)。有 8 项研究观察到干预组与对照组相比有统计学意义的结果。其中只有一项研究显示治疗效果持续超过一年。
没有足够的数据可以得出结论,即 LHW 干预对 RMD 患者是否有积极、中性或消极的影响。未来的 LHW 干预措施应预先确定假设,为主要结果的统计学意义提供动力,采用理论框架,包括积极的对照,描述 LHW 的培训方案,并增加少数族裔的代表性,以确定 LHW 对 RMD 患者的有效性。