Clark D C, Stamm J W, Quee T C, Robert G
Community Dent Oral Epidemiol. 1985 Apr;13(2):61-4. doi: 10.1111/j.1600-0528.1985.tb01676.x.
The purpose of this study was to demonstrate the effectiveness of two fluoride varnishes (Duraphat and Fluor Protector) in the prevention of dental caries in children residing in a non-fluoridated community. At baseline, 787 grade one children (6-7-yr old) were examined and randomly allocated into a control and two treatment groups. At 20 months, 703 children remained in the study. The mean baseline caries experience and the mean number of permanent teeth present at 20 months were not significantly different among the treatment and control groups. The mean DMFS increments after 20 months were 1.70, 1.73 and 2.02 for Fluor-Protector, Duraphat and control groups respectively (% reductions of 15.8 and 14.4 for Fluor-Protector and Duraphat groups). The mean dfs increments for primary molars after 20 months were 1.56, 1.62 and 1.74 for Fluor-Protector, Duraphat and control groups respectively (% reductions of 10 for Fluor-Protector and 7 for Duraphat).
本研究的目的是证明两种氟化物漆(Duraphat和氟保护漆)在预防居住于无氟社区儿童龋齿方面的有效性。在基线时,对787名一年级儿童(6 - 7岁)进行了检查,并随机分为一个对照组和两个治疗组。在20个月时,703名儿童仍参与该研究。治疗组和对照组之间,基线时的平均龋齿经历以及20个月时恒牙的平均数量并无显著差异。20个月后,氟保护漆组、Duraphat组和对照组的平均DMFS增量分别为1.70、1.73和2.02(氟保护漆组和Duraphat组的降低百分比分别为15.8和14.4)。20个月后,氟保护漆组、Duraphat组和对照组乳磨牙的平均dfs增量分别为1.56、1.62和1.74(氟保护漆组降低10,Duraphat组降低7)。