Evaluation of Free Radical Scavenging and Antimicrobial Activity of Coleus amboinicus-Mediated Iron Oxide Nanoparticles.

Background In this research, iron oxide nanoparticles were synthesized using stem extract, which is used for various diseases such as throat infection, cough, fever, nasal congestion, and digestive problems.  Aim This study aimed to formulate a green synthesis of iron oxide nanoparticles mediated by (known as karpuravalli in Tamil) and assess its antimicrobial and antioxidant properties.  Materials and methods Iron oxide nanoparticles were synthesized, and then their antimicrobial properties were tested against two specific pathogens, i.e., and using the agar well diffusion technique. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, hydroxyl radical scavenging (HO) assay, and ferric ion reducing antioxidant power (FRAP) assay were conducted to check the free radical scavenging activity.  Result The results obtained showed that these iron oxide nanoparticles showed better antimicrobial activity against when compared to and the antioxidant activity showed a very close efficacy when compared to the standard.  Conclusion The research has demonstrated the high antioxidant activity and high antibacterial activity of iron oxide nanoparticles using stem anatural and cheaper antimicrobial drug compared to the drugs present on the market.