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量化自我管理言语治疗中的剂量:在真实世界移动健康数据集探索累积干预强度的组成部分。

Quantifying Dosage in Self-Managed Speech-Language Therapy: Exploring Components of Cumulative Intervention Intensity in a Real-World Mobile Health Data Set.

机构信息

Department of Speech, Language & Hearing Sciences, Boston University, MA.

出版信息

Am J Speech Lang Pathol. 2024 May;33(3):1513-1523. doi: 10.1044/2024_AJSLP-23-00285. Epub 2024 Apr 4.

Abstract

PURPOSE

Cumulative Intervention Intensity (CII) is a proposed framework for conceptualizing and calculating dose that has been used to quantify intensity of speech-language therapy (SLT) in highly controlled laboratory studies and clinical trials. However, it is unknown whether CII can be applied to characterize the practice patterns of patients undertaking at-home, self-managed SLT. The current study leverages real-world mobile health data to investigate the applicability of CII parameters to self-managed SLT, including the interrelationships between individual CII parameters and their utility for identifying naturally occurring subgroups of patient users.

METHOD

Anonymized data from 2,223 poststroke survivors who used the Constant Therapy application were analyzed. Four quantitative CII parameters-dose, session frequency, session duration, and total intervention duration-were calculated per user over a 3-month analysis period using raw session-level data. We conducted correlation analyses at the level of the individual and group to examine the degree of relatedness between each of the CII parameters. CII parameter measures were additionally used as inputs to a k-mean clustering analysis to identify practice pattern subgroups.

RESULTS

Results demonstrate the feasibility of calculating components of CII based on available usage statistics from a commercial app for self-managed SLT. Specifically, results suggest that, although CII parameters are related, session frequency offers complementary and nonoverlapping information (cf. dose, session duration, total intervention duration) about dosage. Clustering results show that practice patterns can be broadly differentiated according to the (a) amount and (b) frequency of practice.

CONCLUSIONS

The calculation of CII may provide both users and clinicians with a fuller picture of at-home, self-managed practice habits than looking at any one dosage component alone. The study represents a first step toward more comprehensive and theoretically grounded dose reporting for self-managed SLT.

SUPPLEMENTAL MATERIAL

https://doi.org/10.23641/asha.25511191.

摘要

目的

累积干预强度(CII)是一个用于概念化和计算剂量的框架,已被用于量化高度受控的实验室研究和临床试验中的言语治疗(SLT)强度。然而,尚不清楚 CII 是否可用于描述接受家庭自我管理 SLT 的患者的实践模式。本研究利用真实世界的移动健康数据来研究 CII 参数应用于自我管理 SLT 的适用性,包括个体 CII 参数之间的相互关系及其用于识别患者用户自然发生亚组的效用。

方法

分析了 2223 名中风后幸存者使用 Constant Therapy 应用程序的数据。每位用户在 3 个月的分析期内,使用原始会话级数据计算了四个定量 CII 参数 - 剂量、会话频率、会话持续时间和总干预持续时间。我们在个体和群体水平上进行了相关性分析,以检查每个 CII 参数之间的相关性程度。CII 参数测量值还被用作 k-均值聚类分析的输入,以识别实践模式亚组。

结果

结果表明,基于商业自我管理 SLT 应用程序的可用使用统计信息,计算 CII 组成部分是可行的。具体而言,结果表明,尽管 CII 参数是相关的,但会话频率提供了剂量的补充且不重叠的信息(与剂量、会话持续时间、总干预持续时间相比)。聚类结果表明,可以根据(a)练习的量和(b)频率来广泛区分实践模式。

结论

与单独查看任何一个剂量成分相比,CII 的计算可能为家庭自我管理实践习惯的用户和临床医生提供更全面的了解。该研究代表了自我管理 SLT 更全面和基于理论的剂量报告的第一步。

补充材料

https://doi.org/10.23641/asha.25511191.

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