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哮喘应用程序作为促进哮喘患者负责任地使用短效β2-激动剂的新方法:一项混合方法试点研究的结果。

The Asthma App as a New Way to Promote Responsible Short-Acting Beta2-Agonist Use in People With Asthma: Results of a Mixed Methods Pilot Study.

机构信息

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, Netherlands.

National eHealth Living Lab, Leiden, Netherlands.

出版信息

JMIR Hum Factors. 2024 Apr 4;11:e54386. doi: 10.2196/54386.

Abstract

BACKGROUND

Approximately 262 million people worldwide are affected by asthma, and the overuse of reliever medication-specifically, short-acting beta2-agonist (SABA) overuse-is common. This can lead to adverse health effects. A smartphone app, the Asthma app, was developed via a participatory design to help patients gain more insight into their SABA use through monitoring and psychoeducation.

OBJECTIVE

This pilot study aims to evaluate the feasibility and usability of the app. The preliminary effects of using the app after 3 months on decreasing asthma symptoms and improving quality of life were examined.

METHODS

A mixed methods study design was used. Quantitative data were collected using the app. Asthma symptoms (measured using the Control of Allergic Rhinitis and Asthma Test) and the triggers of these symptoms were collected weekly. Quality of life (36-Item Short-Form Health Survey) was assessed at baseline and after 3, 6, and 12 months. User experience (System Usability Scale) was measured at all time points, except for baseline. Furthermore, objective user data were collected, and qualitative interviews, focusing on feasibility and usability, were organized. The interview protocol was based on the Unified Theory of Acceptance and Use of Technology framework. Qualitative data were analyzed using the Framework Method.

RESULTS

The baseline questionnaire was completed by 373 participants. The majority were female (309/373, 82.8%), with a mean age of 46 (SD 15) years, and used, on average, 10 SABA inhalations per week. App usability was rated as good: 82.3 (SD 13.2; N=44) at 3 months. The Control of Allergic Rhinitis and Asthma Test score significantly improved at 3 months (18.5) compared with baseline (14.8; β=.189; SE 0.048; P<.001); however, the obtained score still indicated uncontrolled asthma. At 3 months, there was no significant difference in the quality of life. Owing to the high dropout rate, insufficient data were collected at 6 and 12 months and were, therefore, not further examined. User data showed that 335 users opened the app (250/335, 74.6%, were returning visitors), with an average session time of 1 minute, and SABA registration was most often used (7506/13,081, 57.38%). Qualitative data (from a total of 4 participants; n=2, 50% female) showed that the participants found the app acceptable and clear. Three participants stated that gaining insight into asthma and its triggers was helpful. Two participants no longer used the app because they perceived their asthma as controlled and, therefore, did not use SABA often or only used it regularly based on the advice of the pulmonologist.

CONCLUSIONS

The initial findings regarding the app's feasibility and usability are encouraging. However, the notable dropout rate underscores the need for a cautious interpretation of the results. Subsequent studies, particularly those focusing on implementation, should explore the potential integration of the app into standard treatment practices.

摘要

背景

全球约有 2.62 亿人受哮喘影响,过度使用缓解药物,特别是短效β2-激动剂(SABA)的情况较为常见。这可能会导致不良的健康影响。一款名为“哮喘”的智能手机应用程序是通过参与式设计开发的,旨在通过监测和心理教育帮助患者更好地了解自己的 SABA 使用情况。

目的

本试点研究旨在评估该应用程序的可行性和可用性。还检查了使用该应用程序 3 个月后对减少哮喘症状和改善生活质量的初步效果。

方法

采用混合方法研究设计。使用应用程序收集定量数据。每周收集哮喘症状(使用过敏性鼻炎和哮喘控制测试测量)和这些症状的诱因。在基线和 3、6 和 12 个月时评估生活质量(36 项简短健康调查)。用户体验(系统可用性量表)在所有时间点进行测量,但基线除外。此外,还收集了客观的用户数据,并组织了重点关注可行性和可用性的定性访谈。访谈协议基于统一接受和使用技术理论框架。定性数据使用框架方法进行分析。

结果

基线调查问卷由 373 名参与者完成。大多数参与者为女性(309/373,82.8%),平均年龄为 46(SD 15)岁,平均每周使用 10 次 SABA 吸入剂。应用程序的可用性被评为良好:3 个月时为 82.3(SD 13.2;N=44)。与基线相比,过敏性鼻炎和哮喘控制测试评分在 3 个月时显著改善(18.5 分比 14.8 分;β=.189;SE 0.048;P<.001);然而,获得的分数仍表明哮喘未得到控制。3 个月时,生活质量没有显著差异。由于高辍学率,6 个月和 12 个月的数据收集不足,因此未进一步检查。用户数据显示,有 335 名用户打开了该应用程序(250/335,74.6%为回头客),平均会话时间为 1 分钟,SABA 注册最常使用(7506/13081,57.38%)。定性数据(来自总共 4 名参与者;n=2,50%为女性)表明,参与者认为该应用程序可以接受且清晰。三名参与者表示,了解哮喘及其诱因很有帮助。两名参与者不再使用该应用程序,因为他们认为自己的哮喘得到了控制,因此不经常使用 SABA,或者仅根据肺科医生的建议定期使用。

结论

该应用程序的可行性和可用性的初步结果令人鼓舞。然而,显著的辍学率突显了谨慎解释结果的必要性。后续研究,特别是关注实施的研究,应探索将该应用程序纳入标准治疗实践的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e93/11027062/797e0b24851b/humanfactors_v11i1e54386_fig1.jpg

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