变形杆菌属血流感染：三种变形杆菌属比较流行病学。

Proteus species bloodstream infections: Comparative epidemiology of three species.

机构信息

Queensland University of Technology (QUT), Brisbane, Queensland, Australia; Department of Intensive Care Services, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

Queensland University of Technology (QUT), Brisbane, Queensland, Australia.

出版信息

Diagn Microbiol Infect Dis. 2024 Jun;109(2):116286. doi: 10.1016/j.diagmicrobio.2024.116286. Epub 2024 Mar 28.

DOI:10.1016/j.diagmicrobio.2024.116286

PMID:38574445

Abstract

BACKGROUND

Although Proteus species are occasional causes of serious infections, their epidemiology has not been well defined. The objective was to describe the overall and species-specific occurrence and determinants of Proteus species bloodstream infection (BSI) in a large Australian population.

METHODS

All Queensland residents with Proteus species BSI identified within the publicly funded healthcare system between 2000 and 2019 were included.

RESULTS

A total of 2,143 incident episodes of Proteus species BSI were identified among 2,079 Queensland residents. The prevalence of comorbid illness differed with higher Charlson comorbidity scores observed with P. penneri and P. vulgaris, and higher prevalence of liver disease with P. penneri, higher comorbid cancer with P. vulgaris, and lower diabetes and renal disease prevalence with P. mirabilis BSIs.

CONCLUSION

This study provides novel information on the epidemiology of Proteus species BSI.

摘要

背景

尽管变形杆菌属是严重感染的偶发原因，但它们的流行病学尚未得到很好的定义。本研究旨在描述在澳大利亚一个大型人群中变形杆菌属血流感染（BSI）的总体和种特异性发生情况及其决定因素。

方法

在 2000 年至 2019 年期间，对在公共资助的医疗保健系统中发现的所有昆士兰州居民的变形杆菌属 BSI 进行了鉴定。

结果

在 2,079 名昆士兰州居民中，共发现了 2,143 例变形杆菌属 BSI 事件。共病情况的患病率有所不同，与 P. penneri 和 P. vulgaris 相比，Charlson 共病评分更高，与 P. penneri 相比，肝病患病率更高，与 P. vulgaris 相比，癌症共病患病率更高，与 P. mirabilis 相比，糖尿病和肾脏疾病患病率更低。