人子宫中的前列腺素：子宫内膜与子宫肌层之间的相互作用。

Prostaglandins in the human uterus: an interaction between endometrium and myometrium.

作者信息

Cameron I T, Kelly R W, Baird D T

出版信息

Prostaglandins Leukot Med. 1985 Mar;17(3):329-35. doi: 10.1016/0262-1746(85)90122-2.

Abstract

The interaction between the prostaglandin production of the human endometrium and myometrium has been further investigated using intact pieces of endometrium in homogenates of myometrium. There was an increase in the production of 6 oxo PGF, alpha when these tissues were incubated together, whereas there was no change in the production of PGE, PGF2 alpha or 13, 14 dihydro 15 - keto PGF2 alpha. This endometrial - myometrial interaction could have important implications in the pathogenesis of menorrhagia.

摘要

利用子宫肌层匀浆中的完整子宫内膜片，对人子宫内膜和子宫肌层前列腺素生成之间的相互作用进行了进一步研究。当这些组织一起孵育时，6-氧代前列腺素Fα的生成增加，而前列腺素E、前列腺素F2α或13,14-二氢-15-酮前列腺素F2α的生成没有变化。这种子宫内膜-子宫肌层相互作用可能在月经过多的发病机制中具有重要意义。