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转移性巨大基底细胞癌的多学科治疗方法——病例报告

A Multidisciplinary approach to metastatic giant basal cell carcinoma-A case report.

作者信息

Lehto Leo E T, Ristola Marko T, Mäntylä Veera, Pajula Susanna

机构信息

Turku University Hospital, Department of Plastic and General Surgery, Finland.

Satasairaala Hospital, Department of Surgery, Finland.

出版信息

JPRAS Open. 2024 Mar 8;40:190-193. doi: 10.1016/j.jpra.2024.03.003. eCollection 2024 Jun.

DOI:10.1016/j.jpra.2024.03.003
PMID:38577347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10992260/
Abstract

We present a case of a 49-year-old man with a giant basal cell carcinoma of the back, with metastases in the lungs, liver, mediastinum and both adrenal glands. Neoadjuvant vismodegib was administered, after which wide local resection of the tumour was performed. There have been no signs of local recurrence.

摘要

我们报告一例49岁男性患者，其背部患有巨大基底细胞癌，并伴有肺、肝、纵隔及双侧肾上腺转移。给予新辅助维莫德吉治疗，之后对肿瘤进行了广泛局部切除。目前尚无局部复发迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d0/10992260/1c80234046d2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d0/10992260/ef4233a37395/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d0/10992260/1c80234046d2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d0/10992260/ef4233a37395/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d0/10992260/1c80234046d2/gr2.jpg

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本文引用的文献

1
Metastatic Basal Cell Carcinoma of the Skin: A Comprehensive Literature Review, Including Advances in Molecular Therapeutics.转移性皮肤基底细胞癌：全面文献综述，包括分子治疗进展。
Adv Anat Pathol. 2020 Sep;27(5):331-353. doi: 10.1097/PAP.0000000000000267.
2
Diagnosis and treatment of basal cell carcinoma: European consensus-based interdisciplinary guidelines.基底细胞癌的诊断和治疗：基于欧洲共识的跨学科指南。
Eur J Cancer. 2019 Sep;118:10-34. doi: 10.1016/j.ejca.2019.06.003. Epub 2019 Jul 6.
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Guidelines of care for the management of basal cell carcinoma.
《基底细胞癌治疗管理指南》。
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Efficacy and safety of vismodegib in advanced basal-cell carcinoma.维莫德吉治疗晚期基底细胞癌的疗效和安全性。
N Engl J Med. 2012 Jun 7;366(23):2171-9. doi: 10.1056/NEJMoa1113713.
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Australas J Dermatol. 1973 Apr;14(1):53. doi: 10.1111/j.1440-0960.1973.tb00016.x.
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Metastatic basal cell carcinoma: report of twelve cases with a review of the literature.转移性基底细胞癌：12例报告并文献复习
J Am Acad Dermatol. 1991 May;24(5 Pt 1):715-9. doi: 10.1016/0190-9622(91)70108-e.
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Nonmelanoma cancers of the skin.皮肤非黑色素瘤癌症
N Engl J Med. 1992 Dec 3;327(23):1649-62. doi: 10.1056/NEJM199212033272307.