Dodson P M, Kritzinger E E
Trans Ophthalmol Soc U K (1962). 1985;104 ( Pt 2):114-9.
Eighty-seven patients with retinal vein occlusion were investigated for the prevalence of associated conditions, and divided in two groups, young (less than 50 years, n = 40) and an older group (greater than 50 years, n = 47). Young patients had a highly significant decreased prevalence of hypertension compared to the older group (27 per cent versus 62 per cent: P less than 0.001), with hyperlipidaemia being the predominant underlying condition (35 per cent). Four young female patients presenting with retinal vein occlusion were on the contraceptive pill. In the majority of young patients (60 per cent) an underlying medical condition could be identified. Striking ethnic differences in the occurrence of retinal vein occlusion have also been observed in a total of 214 patients referred without prior selection in two major ophthalmological centres over a four year period. Only 3 per cent of patients with retinal vein occlusion were Asian and 2 per cent of West Indian origin. In particular, no West Indian patient has been seen with the central form of venous occlusion. We conclude that hyperlipidaemia, and not hypertension, is the predominant associated medical condition in young patients and that other aetiological factors including the contraceptive pill may be found. Marked ethnic differences have also been observed which may give further insight into the exact aetiology of retinal vein occlusion.
对87例视网膜静脉阻塞患者进行了相关疾病患病率的调查，并将其分为两组，年轻组（年龄小于50岁，n = 40）和老年组（年龄大于50岁，n = 47）。与老年组相比，年轻患者高血压患病率显著降低（27%对62%：P < 0.001），高脂血症是主要的潜在疾病（35%）。4例患有视网膜静脉阻塞的年轻女性患者正在服用避孕药。在大多数年轻患者（60%）中，可以确定存在潜在的内科疾病。在四年期间，在两个主要眼科中心未经预先挑选转诊的总共214例患者中，也观察到了视网膜静脉阻塞发生率的显著种族差异。视网膜静脉阻塞患者中只有3%为亚洲人，2%为西印度裔。特别是，未发现西印度裔患者患有中央型静脉阻塞。我们得出结论，高脂血症而非高血压是年轻患者主要的相关内科疾病，并且可能发现包括避孕药在内的其他病因。还观察到了显著的种族差异，这可能有助于进一步深入了解视网膜静脉阻塞的确切病因。
