Luchaogang Community Health Service Center, Pudong New Area, Shanghai, China.
The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Medicine (Baltimore). 2024 Apr 5;103(14):e37382. doi: 10.1097/MD.0000000000037382.
Cervical spondylotic radiculopathy is currently one of the common orthopedic diseases, mainly characterized by neck pain, stiffness, limited mobility, and related symptoms of nerve root compression, which seriously troubles people's work and life.
Ninety cases of cervical spondylotic radiculopathy (Qi stagnation and blood stasis syndrome) were randomly divided into treatment group and control group, 45 cases in each group. The control group was treated with western medicine (nerve nutrition, pain relief, and circulation improvement drugs), and the treatment group was treated with Gao's nape needle combined with modified Shentong Zhuyu decoction on the basis of the control group. Before and after 2 weeks, TCM syndrome score, TCM curative effect, visual analogue scale score, numbness score, neck disability index score, related serum inflammatory factors (interleukin-10 [IL-10], interleukin-6 [IL-6], tumor necrosis factor-α [TNF-α]), related hemorheological indexes (plasma viscosity, high shear whole blood viscosity, low shear whole blood viscosity level) were used as evaluation indexes to evaluate the effect.
After treatment, the total effective rate of the treatment group was 91.11%, which was better than that of the control group (78.78%), and the TCM syndrome scores of the 2 groups were decreased, the treatment group was better than that of the control group, and the differences were statistically significant (P < .05). After treatment, the visual analogue scale score, numbness score, and neck disability index score were decreased in both groups, and the decrease in the treatment group was more significant than that in the control group, and the differences were statistically significant (P < .05). After treatment, the related serum inflammatory factors (IL-10, IL-6, TNF-α) and related hemorheological indexes (plasma viscosity, high-shear whole blood viscosity, low-shear whole blood viscosity) were decreased in both groups, and the decrease in the treatment group was more significant than that in the control group, and the differences were statistically significant (P < .05).
The treatment of cervical spondylotic radiculopathy (Qi stagnation and blood stasis syndrome) with Gao's nape needle and modified Shentong Zhuyu decoction can improve the curative effect of traditional Chinese medicine, improve the related discomfort symptoms (neck tenderness, adverse activity, numbness, etc), improve the neck function, reduce IL-10, IL-6, TNF-α, and other related serum inflammatory factors, and improve hemorheological indicators.
神经根型颈椎病目前是常见的骨科疾病之一,主要表现为颈痛、僵硬、活动受限及神经根受压相关症状,严重困扰人们的工作和生活。
将 90 例神经根型颈椎病(气滞血瘀证)患者随机分为治疗组和对照组,每组 45 例。对照组采用西医(神经营养、止痛、改善循环药物)治疗,治疗组在对照组的基础上采用高氏项针配合加味身痛逐瘀汤治疗。分别于治疗前、治疗 2 周后,采用中医证候评分、中医疗效、视觉模拟评分法(VAS)评分、麻木评分、颈障指数评分、相关血清炎性因子(白细胞介素-10[IL-10]、白细胞介素-6[IL-6]、肿瘤坏死因子-α[TNF-α])、相关血液流变学指标(血浆黏度、高切全血黏度、低切全血黏度水平)作为评价指标,评价疗效。
治疗后,治疗组总有效率为 91.11%,优于对照组的 78.78%,两组中医证候评分均降低,且治疗组优于对照组,差异均有统计学意义(P<0.05)。治疗后,两组 VAS 评分、麻木评分、颈障指数评分均降低,且治疗组降低更明显,差异均有统计学意义(P<0.05)。治疗后,两组相关血清炎性因子(IL-10、IL-6、TNF-α)及相关血液流变学指标(血浆黏度、高切全血黏度、低切全血黏度)均降低,且治疗组降低更明显,差异均有统计学意义(P<0.05)。
高氏项针配合加味身痛逐瘀汤治疗神经根型颈椎病(气滞血瘀证)能提高中医疗效,改善颈痛、活动不利、麻木等相关不适症状,改善颈部功能,降低 IL-10、IL-6、TNF-α 等相关血清炎性因子,改善血液流变学指标。