Zhang Yiming, Dong Liqiang, Zhang Yaoping, Shan Yunping
Orthopedics and Traumatology Department, Hangzhou Fuyang Hospital of TCM Orthopedics and Traumatology Hangzhou, Zhejiang, China.
Orthopedics and Traumatology Department, The Second Affiliated Hospital of Zhejiang Chinese Medicine University Hangzhou, Zhejiang, China.
Am J Transl Res. 2023 Aug 15;15(8):5347-5355. eCollection 2023.
To explore the effect of modified Guizhi plus Gegen decoction combined with the blade needle therapy on traditional Chinese medicine (TCM) syndromes, cervical curvature, and inflammatory factor levels in patients with cervical spondylotic radiculopathy.
In this retrospective study, 114 patients with cervical spondylotic radiculopathy who visited Pain Clinic, Hangzhou Fuyang Hospital of TCM Orthopedics and Traumatology from January 2020 to December 2022 were selected as the study subjects. According to different treatment methods, these patients were divided into an observation group (n=57, treated with blade needle therapy) and a control group (n=57, treated with modified Guizhi plus Gegen decoction combined with the blade needle therapy). Patients in both groups were treated for 3 courses. The treatment effects, TCM syndrome scores, cervical curvature, hemorheology indexes, inflammatory factors and adverse reactions were analyzed and compared between the two groups.
The effective rate of patients in the observation group was 94.74%, which was significantly higher than 82.46% in the control group (P<0.05). After treatment, TCM syndrome scores, hemorheology indexes, and inflammatory factors levels in both of groups were significantly decreased in contrast to before treatment, while the cervical curvature was obviously increased. Compared with the control group, after the treatment, TCM syndrome scores, hemorheology indexes, inflammatory factors levels after treatment in the observation group were obviously lower, while the cervical curvature in the observation group being significantly increased (all P<0.05). No statistical differences were found for the incidence of adverse reactions between two the groups.
Modified Guizhi plus Gegen decoction combined with the blade needle therapy effectively improved the TCM syndrome scores, restored the curvature of the cervical spine, improved the hemorheology of patients, inhibited the levels of inflammatory factors and it also has few adverse reactions, with a significant treatment effect in patients with cervical spondylotic radiculopathy.
探讨加味桂枝加葛根汤联合刃针疗法对神经根型颈椎病患者中医证候、颈椎曲度及炎症因子水平的影响。
本回顾性研究选取2020年1月至2022年12月在杭州市富阳中医骨伤医院疼痛科就诊的114例神经根型颈椎病患者作为研究对象。根据治疗方法不同,将这些患者分为观察组(n = 57,采用刃针疗法治疗)和对照组(n = 57,采用加味桂枝加葛根汤联合刃针疗法治疗)。两组患者均治疗3个疗程。分析比较两组患者的治疗效果、中医证候评分、颈椎曲度、血液流变学指标、炎症因子及不良反应。
观察组患者的有效率为94.74%,显著高于对照组的82.46%(P < 0.05)。治疗后,两组患者的中医证候评分、血液流变学指标及炎症因子水平均较治疗前显著降低,而颈椎曲度明显增加。与对照组相比,治疗后观察组患者的中医证候评分、血液流变学指标及炎症因子水平明显更低,而观察组颈椎曲度显著增加(均P < 0.05)。两组患者不良反应发生率比较,差异无统计学意义。
加味桂枝加葛根汤联合刃针疗法能有效改善神经根型颈椎病患者的中医证候评分,恢复颈椎曲度,改善患者血液流变学,抑制炎症因子水平,且不良反应少,对神经根型颈椎病患者有显著治疗效果。