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小儿肝血管肉瘤合并消耗性甲状腺功能减退——在评估肝脏血管肿瘤时需避免的一个重要诊断陷阱。

Paediatric hepatic angiosarcoma with consumptive hypothyroidism-an important diagnostic pitfall to avoid during evaluation of hepatic vascular tumours.

作者信息

Fenn Dickson, Fung Kin Fen Kevin, Liu Anthony Pak-Yin, Ng Wai Fu, Kan Yee-Ling Elaine

机构信息

Department of Diagnostic and Interventional Radiology, Kwong Wah Hospital, Kowloon Bay, Hong Kong.

Department of Radiology, Hong Kong Children's Hospital, Kowloon Bay, Hong Kong.

出版信息

Pediatr Radiol. 2024 May;54(6):1040-1048. doi: 10.1007/s00247-024-05915-7. Epub 2024 Apr 6.

Abstract

Hepatic angiosarcoma is an extremely rare primary malignant vascular tumour in children with very poor prognosis. Radiological diagnosis of hepatic angiosarcoma is challenging due to overlapping imaging features with other benign vascular hepatic tumours, particularly infantile hepatic haemangioma. Consumptive hypothyroidism is a condition that is almost exclusively associated with infantile hepatic haemangioma and has never been reported in angiosarcoma. We present a case of hepatic angiosarcoma in a 20-month-old girl, associated with consumptive hypothyroidism and, as a result, initially misdiagnosed as infantile hepatic haemangioma. Radiologists should be aware that consumptive hypothyroidism is not a reliable feature to use in excluding paediatric hepatic angiosarcoma. Biopsy should be performed in patients older than 1 year of age or with atypical imaging features.

摘要

肝血管肉瘤是一种极其罕见的儿童原发性恶性血管肿瘤,预后极差。由于其影像学特征与其他良性肝脏血管肿瘤(尤其是婴儿肝血管瘤)重叠,肝血管肉瘤的放射学诊断具有挑战性。消耗性甲状腺功能减退几乎仅与婴儿肝血管瘤相关,从未在血管肉瘤中报道过。我们报告一例20个月大女孩的肝血管肉瘤,该病例伴有消耗性甲状腺功能减退,因此最初被误诊为婴儿肝血管瘤。放射科医生应意识到,消耗性甲状腺功能减退并非排除小儿肝血管肉瘤的可靠特征。对于1岁以上或具有非典型影像学特征的患者,应进行活检。

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