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妊娠晚期睡眠障碍:与引产的关联。

Sleep disturbances in late pregnancy: associations with induction of labor.

机构信息

Department of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Savitehtaankatu 5, 20521, Turku, Finland.

FinnBrain Birth Cohort Study, Department of Clinical Medicine, Turku Brain and Mind Center, University of Turku, Turku, Finland.

出版信息

Arch Gynecol Obstet. 2024 Oct;310(4):2045-2053. doi: 10.1007/s00404-024-07492-4. Epub 2024 Apr 5.

Abstract

PURPOSE

Sleep disturbances, which are common during pregnancy, may compromise labor. Nevertheless, little is known about associations between sleep disturbances and the likelihood of ending up induction of labor (IOL). Accordingly, we aimed to evaluate the connections between sleep disturbances during pregnancy and IOL.

METHODS

Altogether 1778 women from the FinnBrain Birth Cohort Study with gestation weeks over 37 + 6 were enrolled in the study. The women were divided into IOL (n = 331) and spontaneous onset of labor (SOL, n = 1447) groups. Sleep disturbances in late pregnancy were evaluated using the Basic Nordic Sleep Questionnaire. Logistic regression analyses were conducted with adjustments for age, body mass index, parity, smoking, and depressive symptoms.

RESULTS

Sleep disturbances were frequent in both IOL and SOL groups. In the IOL group 43.0% and in the SOL group 39.0% had poor general sleep quality (P = 0.186). Nocturnal awakenings occurred most commonly, in 94.0% and 93.9%, respectively (P = 0.653). In the IOL group, more women (22.7%) were habitual snorers than in the SOL group (17.0%, P = 0.017), however, the difference lost the statistical significance in adjusted analysis (P = 0.848). Women in the IOL group were more likely to be short sleepers (< 7 h) compared to those in the SOL group (20.2% and 15.4%, respectively, P = 0.034) with no difference after adjustment (P = 0.133). The two groups showed no differences in sleep loss (P = 0.252).

CONCLUSIONS

Deterioration in sleep quality was noticeable in pregnant women, but it was unconnected with IOL. As the frequency of IOL is increasing, more research for related risk factors is needed.

摘要

目的

妊娠期间常见的睡眠障碍可能会影响分娩。然而,对于睡眠障碍与诱导分娩(IOL)的可能性之间的关联,我们知之甚少。因此,我们旨在评估妊娠期间睡眠障碍与 IOL 之间的关系。

方法

总共纳入了来自芬兰大脑出生队列研究的 1778 名妊娠周数超过 37+6 周的女性,这些女性被分为 IOL(n=331)和自发性临产(SOL,n=1447)组。使用基本北欧睡眠问卷评估妊娠晚期的睡眠障碍。使用逻辑回归分析进行调整,包括年龄、体重指数、产次、吸烟和抑郁症状。

结果

IOL 和 SOL 组的睡眠障碍都很常见。在 IOL 组中,43.0%的女性和在 SOL 组中 39.0%的女性睡眠质量较差(P=0.186)。夜间觉醒最常见,分别为 94.0%和 93.9%(P=0.653)。在 IOL 组中,更多的女性(22.7%)习惯性打鼾,而在 SOL 组中为 17.0%(P=0.017),然而,调整后差异失去统计学意义(P=0.848)。与 SOL 组相比,IOL 组的女性更有可能睡眠不足(<7 小时)(分别为 20.2%和 15.4%,P=0.034),调整后无差异(P=0.133)。两组的睡眠损失无差异(P=0.252)。

结论

妊娠女性的睡眠质量明显恶化,但与 IOL 无关。随着 IOL 频率的增加,需要更多针对相关危险因素的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a24/11393193/ffd464fa8355/404_2024_7492_Fig1_HTML.jpg

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