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一组甲状腺细针抽吸活检病例被诊断为具有嗜酸细胞特征的滤泡性肿瘤。

A case series of thyroid fine needle aspiration biopsies diagnosed as follicular neoplasm with oncocytic features.

机构信息

Department of Pathology, University of California, San Francisco, San Francisco, California, USA.

出版信息

Diagn Cytopathol. 2024 Oct;52(10):553-557. doi: 10.1002/dc.25314. Epub 2024 Apr 6.

Abstract

Oncocytic lesions of the thyroid are a heterogeneous group encompassing nonneoplastic and neoplastic entities ranging from benign to malignant and have traditionally been classified as separate entities in thyroid pathology. To illustrate the diversity of these thyroid lesions, we describe three cases of fine needle aspiration biopsies (FNAB) diagnosed as Bethesda Category IV: Follicular neoplasm, oncocytic type, under the 2017 Bethesda System for Reporting Thyroid Cytopathology (TBSRTC), with ThyroSeq v3 molecular testing and subsequent surgical excision.

摘要

甲状腺的嗜酸细胞病变是一组异质性病变,包括从良性到恶性的非肿瘤和肿瘤性病变,在甲状腺病理学中传统上被分类为独立的实体。为了说明这些甲状腺病变的多样性,我们描述了三例细针抽吸活检(FNAB),根据 2017 年甲状腺细胞病理学报告的 Bethesda 系统(TBSRTC)诊断为滤泡性肿瘤,嗜酸细胞型,属于 Bethesda 分类第四类,同时进行了 ThyroSeq v3 分子检测,随后进行了手术切除。

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