Yin Yuehui, Tang Shanfang
Department of Radiology, Weifang People's Hospital, Weifang, Shandong, PR China.
Department of Public Health, Weifang People's Hospital, Weifang, Shandong, PR China.
Int J Surg Case Rep. 2024 May;118:109608. doi: 10.1016/j.ijscr.2024.109608. Epub 2024 Apr 4.
Chromophobe renal cell carcinoma (CHRCC) is a rare subtype of renal cancer, accompanied by subcapsular renal hematoma (SRH) without a history of traumatic or hemorrhagic disease, which is clinically rare. The reason for CHRCC with SRH may be caused by tumor rupture or vascular rupture. In the early stage, it is often asymptomatic and can be easily overlooked and misdiagnosed, leading to delayed treatment and serious consequences.
A 39-year-old female patient was admitted to the emergency department due to sudden dull pain and discomfort in the lower back. Subsequent ultrasound, CT, and MRI imaging examinations revealed the presence of chromophobe renal cell carcinoma with a volume of 4.5 × 3.5 × 3 cm in the middle and lower pole of the right kidney. In addition, a subcapsular hematoma with an area of approximately 6 × 11 cm was also found. The patient underwent laparoscopic radical nephrectomy.
Due to its atypical syptmoms and signs, it is often overlooked or misdiagnosed. CHRCC has unique histological features, which distinguish it from other subtypes of renal cell carcinoma. Imaging studies such as CT scan and MRI are helpful in diagnosing and identifying associated complications. In this case, the presence of the perirenal hematoma is a notable finding, which may be caused by tumor-induced vascular disruption.
This report underscores the importance of recognizing and managing complications associated with CHRCC. Early diagnosis and appropriate surgical treatment are crucial for favorable outcomes in these cases.
嫌色性肾细胞癌(CHRCC)是一种罕见的肾癌亚型,伴有肾包膜下血肿(SRH)且无创伤或出血性疾病史,临床上较为少见。CHRCC合并SRH的原因可能是肿瘤破裂或血管破裂。早期通常无症状,容易被忽视和误诊,导致治疗延误并产生严重后果。
一名39岁女性患者因突发下背部钝痛和不适入院。随后的超声、CT和MRI成像检查显示,右肾中下级存在体积为4.5×3.5×3cm的嫌色性肾细胞癌。此外,还发现了一个面积约为6×11cm的包膜下血肿。患者接受了腹腔镜根治性肾切除术。
由于其非典型症状和体征,常被忽视或误诊。CHRCC具有独特的组织学特征,使其与肾细胞癌的其他亚型相区别。CT扫描和MRI等影像学检查有助于诊断和识别相关并发症。在本病例中,肾周血肿的存在是一个显著发现,可能是由肿瘤引起的血管破裂所致。
本报告强调了认识和处理与CHRCC相关并发症的重要性。早期诊断和适当的手术治疗对于这些病例取得良好预后至关重要。