Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Department of Psychiatry, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Contraception. 2024 Jul;135:110447. doi: 10.1016/j.contraception.2024.110447. Epub 2024 Apr 5.
Depression is common during pregnancy and the year following childbirth (the perinatal period). This study assessed the association of depressive symptoms and contraception decisions in perinatal individuals.
We conducted a secondary analysis using data from the PRogram in Support of Moms (PRISM) study, a cluster randomized controlled trial of active interventions which aimed to address perinatal depression. This analysis included 191 individuals aged 18-45 who screened positive for depression on the Edinburgh Postnatal Depression Scale (EPDS, score ≥10) during pregnancy or up to 3 months postpartum. We assessed contraception intent and method choice at 1-3 months postpartum. At 5-7 months postpartum, we assessed contraceptive method used and EPDS depression scores. We used logistic regressions to examine the relationship between depression and contraceptive use/method.
At 1-3 months postpartum, the majority of participants (76.4%) expressed an intention to use contraception. Of those, over half (53.4%) indicated a preference for higher effectiveness contraception methods. Participants with persistent depression symptoms (positive EPDS) at 5-7 months were significantly less likely to report using higher effectiveness contraceptive methods (aOR = 0.28, 95% CI = 0.11-0.70) compared to those without. Among participants with persistent depressive symptoms, 21.1% reported using a contraception method of lower effectiveness than had originally intended.
Perinatal individuals with persistent depressive symptoms at 5-7 months postpartum reported greater use of less-effective contraception methods than originally planned.
We found associations between perinatal depression and use of less effective contraception use. Provider discussions regarding contraception planning is important, particularly in those with perinatal depression symptoms.
抑郁在妊娠和产后一年期间(围产期)很常见。本研究评估了围产期个体抑郁症状与避孕决策的关系。
我们使用 PRogram in Support of Moms (PRISM) 研究的数据进行了二次分析,该研究是一项旨在解决围产期抑郁的积极干预的集群随机对照试验。该分析包括 191 名年龄在 18-45 岁之间的个体,他们在妊娠期间或产后 3 个月内通过 Edinburgh Postnatal Depression Scale(EPDS,评分≥10)筛查出患有抑郁症。我们在产后 1-3 个月评估避孕意愿和方法选择。在产后 5-7 个月,我们评估了避孕方法的使用和 EPDS 抑郁评分。我们使用逻辑回归检验抑郁与避孕使用/方法之间的关系。
在产后 1-3 个月,大多数参与者(76.4%)表示有意使用避孕措施。其中,超过一半(53.4%)表示更喜欢更有效的避孕方法。在产后 5-7 个月时持续出现抑郁症状(EPDS 阳性)的参与者,与没有抑郁症状的参与者相比,报告使用更有效的避孕方法的可能性显著降低(优势比[OR] = 0.28,95%置信区间[CI] = 0.11-0.70)。在持续出现抑郁症状的参与者中,21.1%报告使用的避孕方法比最初计划的效果要差。
产后 5-7 个月时持续出现抑郁症状的围产期个体报告使用了比最初计划效果更差的避孕方法。
我们发现围产期抑郁与使用效果较差的避孕方法之间存在关联。在提供避孕计划相关讨论时,特别是在那些有围产期抑郁症状的人群中,这一点非常重要。