Department of Gastroenterology, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou, China.
Int Wound J. 2024 Apr;21(4):e14847. doi: 10.1111/iwj.14847.
Due to the high risks of postoperative complications brought on by gastric cancer, traditional Chinese medicine (TCM) as a commonly used therapy, has exerted its vital role in postoperative recovery care. In this sense, this meta-analysis was conducted to explore the related documents about TCM's impact on gastric cancer postoperative recovery. During the research, we explored a total of 1549 results from databases PubMed, China National Knowledge Infrastructure (CNKI), Embase, Cochrane Library and Web of Science (WoS). Thirty-two clinical randomized trials (RCTs) were then selected and analysed for this meta-analysis by using the software RevMan 5.4 (under PRISMA 2020 regulations), with a population of 3178 patients. Data prove that TCM therapy reduced the risks for postoperative complications exposure by an estimated average of 19% (95% CI). Among the complications, TCM therapy suppressed the risks of wound infection and incisional infections by 53% and 48% respectively. Meanwhile, the patient's wound healing duration exhibited a significant reduction compared to those without TCM treatment, with a difference at around 0.74 days (95% CI). TCM also exerted its potential to strengthen the patient's immune and health conditions, leading to a significantly promoted gastrointestinal function in the patients with a shorter duration to release first exhaustion and defecation compared to those with no TCM therapy. In addition, similar promoted phenomena also exist in those patients with TCM therapy in terms of their immunity and nutritional conditions. These facts all indicate a positive impact of TCM therapy in clinical applications.
由于胃癌术后并发症的风险较高,中药(TCM)作为一种常用的治疗方法,在术后康复护理中发挥了重要作用。因此,进行了这项荟萃分析,以探讨 TCM 对胃癌术后恢复影响的相关文献。在研究过程中,我们从数据库 PubMed、中国国家知识基础设施(CNKI)、Embase、Cochrane 图书馆和 Web of Science(WoS)中总共检索到了 1549 个结果。然后,使用 RevMan 5.4 软件(根据 PRISMA 2020 法规)对 32 项临床随机对照试验(RCT)进行了分析,涉及 3178 名患者。数据证明,TCM 疗法使术后并发症的风险降低了约 19%(95%CI)。在这些并发症中,TCM 疗法分别降低了伤口感染和切口感染的风险 53%和 48%。同时,与未接受 TCM 治疗的患者相比,患者的伤口愈合时间显著缩短,差异约为 0.74 天(95%CI)。TCM 还发挥了增强患者免疫和健康状况的潜力,使接受 TCM 治疗的患者胃肠道功能明显恢复,首次排气和排便的时间明显缩短。此外,接受 TCM 治疗的患者在免疫和营养状况方面也存在类似的促进现象。这些事实都表明 TCM 疗法在临床应用中具有积极的影响。