Fernández-Millones M Lucía, Curi-Vilchez Gianelli S, Parodi Jose F, Runzer-Colmenares Fernando M
Carrera de Medicina Humana, Universidad Científica del Sur, Lima, Peru.
Universidad de San Martín de Porres, Facultad de Medicina Humana, Centro de Investigación del envejecimiento (CIEN), Lima, Peru.
Ann Geriatr Med Res. 2024 Dec;28(4):395-400. doi: 10.4235/agmr.24.0026. Epub 2024 Apr 8.
There is evidence that sarcopenia and functionality are closely related. However, the association between geriatric syndromes, such as dependence, on instrumental activities and sarcopenia could be affected by the presence of certain comorbidities, such as overweight, obesity, diabetes, and chronic obstructive pulmonary disease (COPD). Therefore, the present study aimed to determine the association between instrumental activities of daily living and muscle mass in the elderly and evaluate the impact of certain comorbidities on this association.
This was a retrospective analytical observational study, including 1,897 patients. Muscle mass was measured with calf circumference, and instrumental activities were measured with the Lawton index.
Among different parameters studies, a statistical correlation was found in a stratified regression analysis between the Lawton index score and muscle mass in patients who were overweight (p=0.001, β coefficient=0.08), obese (p=0.001, β coefficient=0.05), had diabetes (p=0.012, β coefficient=0.03), and had COPD (p=0.001, β coefficient=0.03).
The correlation between muscle mass and instrumental activities of daily living should be evaluated individually according to the needs of each participant and according to their comorbidities, promoting patient-centered geriatric medicine.
有证据表明肌肉减少症与功能密切相关。然而,诸如依赖等老年综合征与工具性日常生活活动能力和肌肉减少症之间的关联可能会受到某些合并症的影响,如超重、肥胖、糖尿病和慢性阻塞性肺疾病(COPD)。因此,本研究旨在确定老年人的工具性日常生活活动能力与肌肉质量之间的关联,并评估某些合并症对这种关联的影响。
这是一项回顾性分析观察性研究,纳入了1897例患者。通过小腿围测量肌肉质量,通过Lawton指数测量工具性日常生活活动能力。
在不同参数研究中,分层回归分析发现,超重患者(p = 0.001,β系数 = 0.08)、肥胖患者(p = 0.001,β系数 = 0.05)、糖尿病患者(p = 0.012,β系数 = 0.03)和慢性阻塞性肺疾病患者(p = 0.001,β系数 = 0.03)的Lawton指数评分与肌肉质量之间存在统计学相关性。
应根据每个参与者的需求及其合并症,单独评估肌肉质量与工具性日常生活活动能力之间的相关性,以促进以患者为中心的老年医学。