Yuan Han, Kim Maengkyu
Sports Medicine Lab., Department of Physical Education, Graduate School, Kyungpook National University, Daegu, Korea.
Sports Science Research Institute, Kyungpook National University, Daegu, Korea.
Ann Geriatr Med Res. 2023 Dec;27(4):329-337. doi: 10.4235/agmr.23.0101. Epub 2023 Sep 25.
The use of ultrasonographic echo intensity (EI) to evaluate skeletal muscle quality and its effects on strength, explosive power, and physical function (PF) in older individuals remains unclear. This meta-analysis evaluated the associations among EI, muscle strength (MS), and PF in older individuals.
We conducted a systematic search of the PubMed, Embase, Web of Science, SPORT Discus, and CINAHL databases through October 2022 to identify primary studies examining the association between EI and MS/PF. Effect sizes were computed using a random-effects model and presented using forest plots. Pearson correlation coefficient (r) and I2 statistics were used to measure heterogeneity.
This meta-analysis included 24 patients. EI demonstrated a negative association with maximal strength (r=-0.351; 95% confidence interval [CI], -0.411 to -0.288; p<0.001) and explosive power (r=-0.342; 95% CI, -0.517 to -0.139; p=0.001) in older individuals. Handgrip strength also showed a significant negative correlation with EI (r=-0.361; 95% CI, -0.463 to -0.249; p<0.001). However, we observed only a small and non-significant negative association between EI and gait speed (r=-0.003; 95% CI, -0.083 to -0.077; p=0.943), and a weak non-significant correlation with the chair stand test (r=0.072; 95% CI, -0.045 to 0.187; p=0.227).
Increased EI was associated with lower strength and power but not with gait speed or chair test performance in older individuals. Further large-sample studies with long-term follow-up are needed to improve frailty prediction and risk assessment in this population.
使用超声回声强度（EI）评估老年人骨骼肌质量及其对力量、爆发力和身体功能（PF）的影响尚不清楚。本荟萃分析评估了老年人EI、肌肉力量（MS）和PF之间的关联。
我们对截至2022年10月的PubMed、Embase、Web of Science、SPORT Discus和CINAHL数据库进行了系统检索，以确定研究EI与MS/PF之间关联的原始研究。效应量使用随机效应模型计算，并以森林图呈现。Pearson相关系数（r）和I²统计量用于衡量异质性。
本荟萃分析纳入了24名患者。在老年人中，EI与最大力量（r=-0.351；95%置信区间[CI]，-0.411至-0.288；p<0.001）和爆发力（r=-0.342；95%CI，-0.517至-0.139；p=0.001）呈负相关。握力也与EI呈显著负相关（r=-0.361；95%CI，-0.463至-0.249；p<0.001）。然而，我们仅观察到EI与步速之间存在微小且不显著的负相关（r=-0.003；95%CI，-0.083至-0.077；p=0.943），与椅子起立测试之间存在微弱且不显著的相关性（r=0.072；95%CI，-0.045至0.187；p=0.227）。
EI升高与老年人较低的力量和功率相关，但与步速或椅子测试表现无关。需要进一步进行长期随访的大样本研究，以改善该人群的衰弱预测和风险评估。
