Sun Chuang, Li Jie, Zhao Zeyuan, Ren Shupeng, Guan Yue, Zhang Miaoan, Li Tianfeng, Tan Linglin, Yao Qiying, Chen Liang
Department of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
General Practice Department, The First Affiliated Hospital of Yangtze University, Jingzhou, China.
Front Nutr. 2024 Mar 22;11:1363574. doi: 10.3389/fnut.2024.1363574. eCollection 2024.
OBJECTIVE: Extensive research has consistently shown the beneficial impact of fruit consumption on overall health. While some studies have proposed a potential association between fruit consumption and hypertension management, the influence of fruit consumption on mortality rates among hypertensive individuals remains uncertain. Consequently, aim of this study is to evaluate whether fruit consumption is associated with all-cause mortality among hypertensive patients. METHODS: Data were obtained from the National Health and Nutrition Examination Survey (NHANES), conducted between 2003 and 2006. Ten-year follow-up data from the National Death Index (NDI) were used to assess all-cause mortality. Cox proportional hazard model was utilized to explore the impact of fruit intake on all-cause mortality among hypertensive individuals. RESULTS: The study included a cohort of 2,480 patients diagnosed with hypertension, and during the follow-up period, a total of 658 deaths from various causes were recorded. The COX regression analysis demonstrated that hypertensive patients who consumed apples three to six times per week exhibited a significantly reduced risk of all-cause mortality (HR = 0.60, 95%CI: 0.45-0.78, < 0.001) in comparison to those who consumed apples less than once per month. Likewise, consuming bananas three to six times per week also led to a comparable outcome (HR = 0.76, 95%CI: 0.59-0.97, = 0.027). Moreover, Combined consumption of bananas and apples three to six times per week exhibited a noteworthy decrease in all-cause mortality (HR = 0.57, 95%CI: 0.39-0.84, = 0.005) when compared to individuals who consumed these fruits less frequently. Conversely, no significant association was found between the consumption of other fruits, including pears, pineapples, and grapes, and all-cause mortality. CONCLUSION: The study discovered that moderate consumption of apples and bananas was associated with a reduced risk of all-cause mortality in patients with hypertension.
目的:大量研究一直表明食用水果对整体健康有益。虽然一些研究提出了食用水果与高血压管理之间可能存在关联,但食用水果对高血压患者死亡率的影响仍不确定。因此,本研究的目的是评估食用水果是否与高血压患者的全因死亡率相关。 方法:数据来自2003年至2006年进行的美国国家健康和营养检查调查(NHANES)。使用来自国家死亡指数(NDI)的十年随访数据来评估全因死亡率。采用Cox比例风险模型探讨水果摄入量对高血压个体全因死亡率的影响。 结果:该研究纳入了2480名被诊断患有高血压的患者队列,在随访期间,共记录了658例各种原因导致的死亡。COX回归分析表明,与每月食用苹果少于一次的高血压患者相比,每周食用三至六次苹果的患者全因死亡率风险显著降低(HR = 0.60,95%CI:0.45 - 0.78,P < 0.001)。同样,每周食用三至六次香蕉也导致了类似的结果(HR = 0.76,95%CI:0.59 - 0.97,P = 0.027)。此外,与食用这些水果频率较低的个体相比,每周三至六次同时食用香蕉和苹果的患者全因死亡率显著降低(HR = 0.57,95%CI:0.39 - 0.84,P = 0.005)。相反,未发现食用其他水果(包括梨、菠萝和葡萄)与全因死亡率之间存在显著关联。 结论:该研究发现适度食用苹果和香蕉与高血压患者全因死亡率风险降低有关。
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