Tutelman Perri R, MacKenzie Nicole E, Chambers Christine T, Coffman Siobhan, Cornelissen Laura, Cormier Brittany, Higgins Kristen S, Phinney Jackie, Blankenburg Markus, Walker Suellen
Department of Psychology and Neuroscience, Dalhousie University, Halifax, Canada.
Centre for Pediatric Pain Research, IWK Health, Halifax, Canada.
Pain Rep. 2024 Apr 3;9(3):e1151. doi: 10.1097/PR9.0000000000001151. eCollection 2024 Jun.
Quantitative sensory testing (QST) refers to a group of noninvasive psychophysical tests that examine responses to a range of calibrated mechanical and thermal stimuli. Quantitative sensory testing has been used extensively in adult pain research and has more recently been applied to pediatric pain research. The aims of this scoping review were to map the current state of the field, to identify gaps in the literature, and to inform directions for future research. Comprehensive searches were run in 5 databases. Titles, abstracts, and full texts were screened by 2 reviewers. Data related to the study aims were extracted and analyzed descriptively. A total of 16,894 unique studies were identified, of which 505 were screened for eligibility. After a full-text review, 301 studies were retained for analysis. Date of publication ranged from 1966 to 2023. However, the majority of studies (61%) were published within the last decade. Studies included participants across the developmental trajectory (ie, early childhood to adolescence) and most often included a combination of school-age children and adolescents (49%). Approximately 23% of studies were conducted in healthy samples. Most studies (71%) used only one QST modality. Only 14% of studies reported using a standardized QST protocol. Quantitative sensory testing in pediatric populations is an emerging and rapidly growing area of pain research. Future work is needed using comprehensive, standardized QST protocols to harness the full potential that this procedure can offer to our understanding of pediatric pain.
定量感觉测试（QST）是指一组非侵入性的心理物理学测试，用于检查对一系列校准的机械和热刺激的反应。定量感觉测试已在成人疼痛研究中广泛应用，最近也被应用于儿科疼痛研究。本范围综述的目的是梳理该领域的现状，找出文献中的空白，并为未来研究指明方向。在5个数据库中进行了全面检索。由2名评审员筛选标题、摘要和全文。提取与研究目的相关的数据并进行描述性分析。共识别出16894项独特研究，其中505项被筛选是否符合纳入标准。经过全文评审，保留301项研究进行分析。发表日期从1966年到2023年。然而，大多数研究（61%）是在过去十年内发表的。研究纳入了不同发育阶段的参与者（即幼儿期到青少年期），最常见的是学龄儿童和青少年的组合（49%）。约23%的研究是在健康样本中进行的。大多数研究（71%）仅使用一种QST模式。只有14%的研究报告使用了标准化的QST方案。儿科人群的定量感觉测试是疼痛研究中一个新兴且快速发展的领域。需要开展进一步工作，使用全面、标准化的QST方案，以充分发挥该方法在我们理解儿科疼痛方面的全部潜力。
