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揭开伪装：细针穿刺抽吸诊断临床疑似淋巴瘤的去分化脂肪肉瘤

Unmasking the Masquerade: Fine-Needle Aspiration Diagnosis of Dedifferentiated Liposarcoma Clinically Mimicking Lymphoma.

作者信息

Chadha Prerna, Kapoor Raghav, Agarwal Poojan, Pasricha Sunil, Mehta Anurag

机构信息

Pathology, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, IND.

Pathology, Jawaharlal Nehru Medical College (KLE), Belagavi, IND.

出版信息

Cureus. 2024 Mar 7;16(3):e55759. doi: 10.7759/cureus.55759. eCollection 2024 Mar.

DOI:10.7759/cureus.55759
PMID:38586754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10998977/
Abstract

A preoperative diagnosis of dedifferentiated liposarcomas (DDLPS) on fine-needle aspiration cytology (FNAC) is rare with scarce indexed literature. Herein, we describe a case of DDLPS diagnosed on fine needle aspiration which was presumed to be a lymphoma clinically and radiologically.

摘要

细针穿刺细胞学检查（FNAC）术前诊断去分化脂肪肉瘤（DDLPS）的情况罕见，相关索引文献也很少。在此，我们描述一例通过细针穿刺诊断的DDLPS病例，该病例在临床和放射学上最初被误诊为淋巴瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e047/10998977/b4dd9269a38b/cureus-0016-00000055759-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e047/10998977/cd5706bbedeb/cureus-0016-00000055759-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e047/10998977/b4dd9269a38b/cureus-0016-00000055759-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e047/10998977/cd5706bbedeb/cureus-0016-00000055759-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e047/10998977/b4dd9269a38b/cureus-0016-00000055759-i02.jpg

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本文引用的文献

1
Pitfalls in soft tissue cytopathology.软组织细胞病理学中的陷阱。
Cytopathology. 2024 Jan;35(1):30-47. doi: 10.1111/cyt.13282. Epub 2023 Aug 7.
2
Dedifferentiated liposarcoma with abrupt transition of low-grade and high-grade dedifferentiation: A rare case report.去分化脂肪肉瘤中低级和高级去分化的急剧转变：一例罕见病例报告。
Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211048565. doi: 10.1177/20587384211048565.
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Role of fine needle aspiration cytology in the diagnosis of soft tissue tumours.细针穿刺细胞学在软组织肿瘤诊断中的作用。
Cytopathology. 2020 Jul;31(4):271-279. doi: 10.1111/cyt.12836. Epub 2020 Jun 14.
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Dedifferentiated liposarcoma and pleomorphic liposarcoma: a comparative study of cytomorphology and MDM2/CDK4 expression on fine-needle aspiration.去分化脂肪肉瘤和多形性脂肪肉瘤：细针抽吸细胞学形态学和 MDM2/CDK4 表达的比较研究。
Cancer Cytopathol. 2014 Feb;122(2):128-37. doi: 10.1002/cncy.21362. Epub 2013 Nov 12.
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Liposarcomas: diagnostic pitfalls and new insights.脂肪肉瘤：诊断陷阱与新认识。
Histopathology. 2014 Jan;64(1):38-52. doi: 10.1111/his.12311. Epub 2013 Dec 6.
6
Diagnostic utility of p16, CDK4, and MDM2 as an immunohistochemical panel in distinguishing well-differentiated and dedifferentiated liposarcomas from other adipocytic tumors.p16、CDK4 和 MDM2 的免疫组织化学组合在鉴别高分化和去分化脂肪肉瘤与其他脂肪性肿瘤中的诊断效用。
Am J Surg Pathol. 2012 Mar;36(3):462-9. doi: 10.1097/PAS.0b013e3182417330.
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Update on liposarcoma: a review for cytopathologists.脂肪肉瘤的最新进展：给细胞病理学家的综述
Diagn Cytopathol. 2012 Dec;40(12):1122-31. doi: 10.1002/dc.21794. Epub 2011 Sep 19.
8
Fine needle aspiration biopsy diagnosis of dedifferentiated liposarcoma: Cytomorphology and MDM2 amplification by FISH.细针穿刺活检诊断去分化脂肪肉瘤：细胞形态学及荧光原位杂交检测MDM2基因扩增
Cytojournal. 2010 Apr 6;7:5. doi: 10.4103/1742-6413.62257.