Departments of Radiology, 74678Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Departments of Pathology, 74678Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211048565. doi: 10.1177/20587384211048565.
Dedifferentiated liposarcoma is a unique subtype of liposarcoma, which has obvious histological heterogeneity. In affected patients, the condition typically manifests as the dedifferentiation of high-grade histological morphology, but it may also manifest as the dedifferentiation of low-grade histological morphology. In some cases, unique histological or immunophenotypic characteristics are observed. We describe, herein, a rare case of dedifferentiated liposarcoma, in which the high-grade and low-grade dedifferentiated components coexisted with a relatively sharp transition in pathology.
去分化脂肪肉瘤是一种独特的脂肪肉瘤亚型,具有明显的组织学异质性。在受影响的患者中,该疾病通常表现为高级别组织形态学的去分化,但也可能表现为低级别组织形态学的去分化。在某些情况下,还观察到独特的组织学或免疫表型特征。我们在此描述了一例罕见的去分化脂肪肉瘤病例,其中高级别和低级别去分化成分共存,病理学上具有相对明显的过渡。