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改善血压控制的膳食纤维使用建议。

Recommendations for the Use of Dietary Fiber to Improve Blood Pressure Control.

机构信息

Hypertension Research Laboratory, School of Biological Sciences (H.A.J., M.S., F.Z.M.), Monash University, Melbourne, VIC, Australia.

Victorian Heart Institute (M.S., F.Z.M.), Monash University, Melbourne, VIC, Australia.

出版信息

Hypertension. 2024 Jul;81(7):1450-1459. doi: 10.1161/HYPERTENSIONAHA.123.22575. Epub 2024 Apr 8.

Abstract

According to several international, regional, and national guidelines on hypertension, lifestyle interventions are the first-line treatment to lower blood pressure (BP). Although diet is one of the major lifestyle modifications described in hypertension guidelines, dietary fiber is not specified. Suboptimal intake of foods high in fiber, such as in Westernized diets, is a major contributing factor to mortality and morbidity of noncommunicable diseases due to higher BP and cardiovascular disease. In this review, we address this deficiency by examining and advocating for the incorporation of dietary fiber as a key lifestyle modification to manage elevated BP. We explain what dietary fiber is, review the existing literature that supports its use to lower BP and prevent cardiovascular disease, describe the mechanisms involved, propose evidence-based target levels of fiber intake, provide examples of how patients can achieve the recommended targets, and discuss outstanding questions in the field. According to the evidence reviewed here, the minimum daily dietary fiber for adults with hypertension should be >28 g/day for women and >38 g/day for men, with each extra 5 g/day estimated to reduce systolic BP by 2.8 mm Hg and diastolic BP by 2.1 mm Hg. This would support a healthy gut microbiota and the production of gut microbiota-derived metabolites called short-chain fatty acids that lower BP. Awareness about dietary fiber targets and how to achieve them will guide medical teams on better educating patients and empowering them to increase their fiber intake and, as a result, lower their BP and cardiovascular disease risk.

摘要

根据几项国际、地区和国家的高血压指南,生活方式干预是降低血压(BP)的一线治疗方法。尽管饮食是高血压指南中描述的主要生活方式改变之一,但膳食纤维并未具体说明。膳食纤维摄入不足,例如西方化饮食中,是导致非传染性疾病死亡率和发病率升高的主要因素,这是由于血压升高和心血管疾病导致的。在这篇综述中,我们通过检查和提倡将膳食纤维作为管理升高的 BP 的关键生活方式改变来解决这一不足。我们解释了膳食纤维是什么,回顾了支持其使用来降低 BP 和预防心血管疾病的现有文献,描述了涉及的机制,提出了基于证据的纤维摄入量目标水平,提供了患者如何达到推荐目标的示例,并讨论了该领域的悬而未决的问题。根据这里审查的证据,高血压成年女性的最低每日膳食纤维摄入量应为>28 克/天,男性应为>38 克/天,每天额外摄入 5 克估计可使收缩压降低 2.8 毫米汞柱,舒张压降低 2.1 毫米汞柱。这将支持健康的肠道微生物群和肠道微生物群衍生的代谢物,即短链脂肪酸的产生,从而降低 BP。对膳食纤维目标及其实现方式的认识将指导医疗团队更好地教育患者,并赋予他们增加膳食纤维摄入量的能力,从而降低 BP 和心血管疾病风险。

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