Campbell N R, Burgess E, Choi B C, Taylor G, Wilson E, Cléroux J, Fodor J G, Leiter L A, Spence D
Division of General Internal Medicine, University of Calgary, Alta.
CMAJ. 1999 May 4;160(9 Suppl):S1-6.
To provide updated, evidence-based recommendations for health care professionals on lifestyle changes to prevent and control hypertension in otherwise healthy adults (except pregnant women).
For people at risk for hypertension, there are a number of lifestyle options that may avert the condition--maintaining a healthy body weight, moderating consumption of alcohol, exercising, reducing sodium intake, altering intake of calcium, magnesium and potassium, and reducing stress. Following these options will maintain or reduce the risk of hypertension. For people who already have hypertension, the options for controlling the condition are lifestyle modification, antihypertensive medications or a combination of these options; with no treatment, these people remain at risk for the complications of hypertension.
The health outcomes considered were changes in blood pressure and in morbidity and mortality rates. Because of insufficient evidence, no economic outcomes were considered.
A MEDLINE search was conducted for the period January 1996 to September 1996 for each of the interventions studied. Reference lists were scanned, experts were polled, and the personal files of the authors were used to identify other studies. All relevant articles were reviewed, classified according to study design and graded according to level of evidence.
A high value was placed on the avoidance of cardiovascular morbidity and premature death caused by untreated hypertension.
BENEFITS, HARMS AND COSTS: Lifestyle modification by means of weight loss (or maintenance of healthy body weight), regular exercise and low alcohol consumption will reduce the blood pressure of appropriately selected normotensive and hypertensive people. Sodium restriction and stress management will reduce the blood pressure of appropriately selected hypertensive patients. The side effects of these therapies are few, and the indirect benefits are well known. There are certainly costs associated with lifestyle modification, but they were not measured in the studies reviewed. Supplementing the diet with potassium, calcium and magnesium has not been associated with a clinically important reduction in blood pressure in people consuming a healthy diet.
(1) It is recommended that health care professionals determine the body mass index (weight in kilograms/[height in metres]2) and alcohol consumption of all adult patients and assess sodium consumption and stress levels in all hypertensive patients. (2) To reduce blood pressure in the population at large, it is recommended that Canadians attain and maintain a healthy body mass index. For those who choose to drink alcohol intake should be limited to 2 or fewer standard drinks per day (maximum of 14/week for men and 9/week for women). Adults should exercise regularly. (3) To reduce blood pressure in hypertensive patients, individualized therapy is recommended. This therapy should emphasize weight loss for overweight patients, abstinence from or moderation in alcohol intake, regular exercise, restriction of sodium intake and, in appropriate circumstances, individualized cognitive behaviour modification to reduce the negative effects of stress.
The recommendations were reviewed by all of the sponsoring organizations and by participants in a satellite symposium of the fourth international Conference on Preventive Cardiology. They are similar to those of the World Hypertension League and the Joint National committee, with the exception of the recommendations on stress management, which are based on new information. They have not been clinically tested.
The Canadian Hypertension Society, the Canadian Coalition for High Blood Pressure Prevention and Control, the Laboratory Centre for Disease Control at health Canada, and the Heart and Stroke Foundation of Canada.
为医护人员提供基于最新证据的建议,指导健康成年人(孕妇除外)通过改变生活方式预防和控制高血压。
对于有高血压风险的人群,有多种生活方式选择可能预防该病——保持健康体重、适度饮酒、锻炼、减少钠摄入、调整钙、镁和钾的摄入量以及减轻压力。遵循这些选择将维持或降低高血压风险。对于已经患有高血压的人群,控制病情的选择包括改变生活方式、使用抗高血压药物或两者结合;若不进行治疗,这些人仍有高血压并发症的风险。
所考虑的健康结果是血压变化以及发病率和死亡率的变化。由于证据不足,未考虑经济结果。
对1996年1月至1996年9月期间每项研究的干预措施进行了MEDLINE检索。查阅了参考文献列表,向专家进行了咨询,并利用作者的个人档案来识别其他研究。对所有相关文章进行了审查,根据研究设计进行分类,并根据证据水平进行分级。
高度重视避免因未治疗的高血压导致的心血管疾病和过早死亡。
益处、危害和成本:通过减肥(或保持健康体重)、定期锻炼和低酒精摄入来改变生活方式,将降低适当选择的血压正常者和高血压患者的血压。限制钠摄入和管理压力将降低适当选择的高血压患者的血压。这些疗法的副作用很少,间接益处众所周知。改变生活方式肯定存在成本,但在所审查的研究中未进行衡量。在健康饮食的人群中,补充钾、钙和镁与临床上显著降低血压无关。
(1)建议医护人员确定所有成年患者的体重指数(体重千克数/[身高米数]²)和酒精摄入量,并评估所有高血压患者的钠摄入量和压力水平。(2)为了在总体人群中降低血压,建议加拿大人达到并维持健康的体重指数。对于选择饮酒的人,每天饮酒量应限制在2标准杯或更少(男性每周最多14杯,女性每周最多9杯)。成年人应定期锻炼。(3)为了降低高血压患者的血压,建议采用个体化治疗。这种治疗应强调超重患者减肥、戒酒或适度饮酒、定期锻炼、限制钠摄入,并在适当情况下进行个体化认知行为改变以减轻压力的负面影响。
这些建议由所有发起组织以及第四届国际预防心脏病学会议卫星研讨会的参与者进行了审查。它们与世界高血压联盟和美国国家联合委员会的建议相似,但关于压力管理的建议基于新信息。它们尚未经过临床测试。
加拿大高血压协会、加拿大高血压预防与控制联盟、加拿大卫生部疾病控制实验室中心以及加拿大心脏与中风基金会。