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耳鼻喉头颈外科 90 岁及以上和百岁老人择期手术趋势及结局的 NSQIP 研究

Elective Surgery Trends and Outcomes of Nonagenarians and Centenarians in Otolaryngology-Head and Neck Surgery: A NSQIP Study.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Sean Parker Institute for the Voice, Weill Cornell Medicine, New York, New York, U.S.A.

Division of Geriatrics and Palliative Medicine, Weill Cornell Medicine, New York, New York, U.S.A.

出版信息

Laryngoscope. 2024 Sep;134(9):3989-3996. doi: 10.1002/lary.31446. Epub 2024 Apr 8.

Abstract

OBJECTIVE

To describe types and outcomes of elective otolaryngological surgeries undergone by patients ≥90 years of age and to assess whether very old age is an independent risk factor for postsurgical complications and death.

METHODS

The National Surgical Quality Improvement Program, a validated national prospective surgical outcomes database, was used to identify all patients aged 65 years and older who underwent elective otolaryngological procedures from 2011 to 2020. Study outcomes included minor complications, major life-threatening complications, and 30-day mortality. Predictors of outcomes, including frailty, were identified using univariable analyses and age was added into the final logistic regression models with stepwise selection.

RESULTS

A total of 40,723 patients met inclusion criteria; 629 (1.5%) patients were ≥90 years of age. Of the 63,389 procedures, head and neck (67.6%) and facial plastics and reconstructive (15.0%) procedures were most common. The overall incidence of major life-threatening complications, minor complications, and death was 2.0%, 3.5%, and 0.4%, respectively. Age ≥90 was significantly associated with an increased risk for 30-day mortality, but not with major or minor postoperative complications. A high modified frailty index was significantly associated with an increased risk for major postoperative complications and death amongst patients ≥90 years.

CONCLUSIONS

Elective otolaryngological surgery can be safe in relatively healthy nonagenarians and centenarians, though there is a small increased risk of 30-day mortality. Although older age can predispose patients to other comorbidities, age alone should not deter surgeons and patients from considering elective otolaryngological procedures. Frailty may be a better predictor for surgical outcomes.

LEVEL OF EVIDENCE

IV Laryngoscope, 134:3989-3996, 2024.

摘要

目的

描述≥90 岁患者接受的选择性耳鼻喉科手术的类型和结果,并评估非常高龄是否是术后并发症和死亡的独立危险因素。

方法

使用国家手术质量改进计划(National Surgical Quality Improvement Program),这是一个经过验证的全国前瞻性手术结果数据库,来确定 2011 年至 2020 年间所有接受择期耳鼻喉科手术的 65 岁及以上患者。研究结果包括轻微并发症、危及生命的重大并发症和 30 天死亡率。使用单变量分析确定结果的预测因素,包括脆弱性,并使用逐步选择将年龄添加到最终的逻辑回归模型中。

结果

共有 40723 名患者符合纳入标准;629 名(1.5%)患者≥90 岁。在 63389 例手术中,头颈部(67.6%)和面部整形与重建(15.0%)手术最为常见。总体上,危及生命的重大并发症、轻微并发症和死亡的发生率分别为 2.0%、3.5%和 0.4%。年龄≥90 岁与 30 天死亡率增加显著相关,但与术后主要或轻微并发症无关。高改良脆弱指数与≥90 岁患者术后发生重大并发症和死亡的风险显著相关。

结论

对于相对健康的非百岁老人和百岁老人来说,择期耳鼻喉科手术是安全的,尽管 30 天死亡率略有增加。尽管年龄较大可能使患者易患其他合并症,但仅年龄不应阻止外科医生和患者考虑择期耳鼻喉科手术。脆弱性可能是手术结果的更好预测指标。

证据等级

IV 喉镜,134:3989-3996,2024。

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