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吞咽困难与髋部骨折手术后的死亡风险增加相关。

Dysphagia is associated with increased mortality risk after hip fracture surgery.

机构信息

Department of Orthopaedic Surgery, University of Virginia, 2280 Ivy Rd, Charlottesville, VA, USA.

出版信息

Eur J Orthop Surg Traumatol. 2024 Jul;34(5):2347-2351. doi: 10.1007/s00590-024-03918-6. Epub 2024 Apr 8.

Abstract

PURPOSE

This study aims to explore the prevalence of dysphagia, as well as mortality associated with dysphagia in the elderly population receiving surgical treatment for a hip fracture.

METHODS

A retrospective cohort study was completed at an academic level 1 tertiary care center. Patients older than or equal to 65 admitted with a hip fracture diagnosis from January 2015 to December 2020 (n = 617) were included. The main outcome was the prevalence of dysphagia and association with mortality. Secondary analysis included timing of dysphagia and contributions to mortality.

RESULTS

Fifty-six percent of patients had dysphagia, and the mortality rates were higher in patients with dysphagia (8.9%) versus those without dysphagia (2.6%), chi-square p = 0.001, and odds ratio 3.69 (CI 1.6-8.5). Mortality rates in patients with acute dysphagia were also higher (12.4%) than those with chronic dysphagia (5%) and chi-squared p = 0.02. Mortality rates in patients with a perioperative dysphagic event (13.9%) were higher than those with non-perioperative dysphagia (4%) and chi-squared p = 0.001. Mortality rates in patients who had acute perioperative dysphagia (21.2%) were higher than those with chronic dysphagia that presented perioperatively (6.8%) and chi-squared p = 0.006.

CONCLUSIONS

This study demonstrates high rates of dysphagia in the elderly hip fracture population and a significant association between dysphagia and mortality. Timing and chronicity of dysphagia were relevant, as patients with acute perioperative dysphagia had the highest mortality rate. Unlike other identified risk factors, dysphagia may be at least partially modifiable. More research is needed to determine whether formal evaluation and treatment of dysphagia lowers mortality risk.

摘要

目的

本研究旨在探讨在接受髋关节骨折手术治疗的老年人群中,吞咽困难的患病率以及与吞咽困难相关的死亡率。

方法

在一家学术水平为 1 级的三级护理中心进行了回顾性队列研究。纳入了 2015 年 1 月至 2020 年 12 月期间因髋关节骨折诊断而入院的年龄在 65 岁及以上的患者(n=617)。主要结局是吞咽困难的患病率以及与死亡率的关系。次要分析包括吞咽困难的发生时间以及对死亡率的影响。

结果

56%的患者存在吞咽困难,且吞咽困难患者的死亡率(8.9%)高于无吞咽困难患者(2.6%),卡方检验 p=0.001,优势比 3.69(95%CI 1.6-8.5)。急性吞咽困难患者的死亡率(12.4%)也高于慢性吞咽困难患者(5%),卡方检验 p=0.02。围手术期发生吞咽困难事件的患者的死亡率(13.9%)高于非围手术期发生吞咽困难的患者(4%),卡方检验 p=0.001。围手术期发生急性吞咽困难的患者的死亡率(21.2%)高于围手术期发生慢性吞咽困难的患者(6.8%),卡方检验 p=0.006。

结论

本研究表明,老年髋关节骨折人群中吞咽困难的发生率较高,且吞咽困难与死亡率之间存在显著关联。吞咽困难的发生时间和慢性程度是相关的,因为围手术期发生急性吞咽困难的患者死亡率最高。与其他已确定的危险因素不同,吞咽困难至少在一定程度上是可以改变的。需要进一步研究以确定是否对吞咽困难进行正式评估和治疗可以降低死亡率风险。

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