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骨折前住院与老年髋部骨折患者更差的功能结局和更高的死亡率相关。

Pre-fracture hospitalization is associated with worse functional outcome and higher mortality in geriatric hip fracture patients.

作者信息

Aigner Rene, Buecking Benjamin, Hack Juliana, Eschbach Daphne, Oberkircher Ludwig, Ruchholtz Steffen, Bliemel Christopher

机构信息

Center for Orthopaedics and Trauma Surgery, University Hospital Marburg, Baldingerstrasse, 35043, Marburg, Germany.

出版信息

Arch Osteoporos. 2017 Dec;12(1):32. doi: 10.1007/s11657-017-0327-2. Epub 2017 Mar 27.

Abstract

UNLABELLED

Hip fractures are common in elderly people. Despite great progress in surgical care, the outcomes of these patients remain disappointing. This study determined pre-fracture hospital admission as a prognostic variable for inferior functional outcomes and increased mortality rates in the perioperative phase and in the first postoperative year.

PURPOSE

The influence of a pre-fracture hospitalization on outcomes in hip fracture patients has not yet been investigated.

METHODS

Four hundred two patients who were surgically treated for hip fracture were prospectively enrolled. Patients with a hospital stay within the last 3 months prior to a hip fracture were compared to patients without a pre-fracture hospitalization. Postoperative functional outcomes and mortality rates were compared between groups at the time of hospital discharge and additionally at the six- and twelve-month follow-up appointments. A multivariate regression analysis was performed.

RESULTS

A pre-fracture hospitalization was reported by 67 patients (17%). In 63% of cases, patients were admitted due to non-surgical, general medical conditions. In 37% of cases, patients were treated due to a condition related to a surgical subject. In the multivariate analysis, pre-fracture hospitalization was an independent risk factor for reduced values on the Barthel Index at 6 months after surgery (B, -9.918; 95%CI of B, -19.001--0.835; p = 0.032) and on the Tinetti Test at 6 months (B, -2.914; 95%CI of B, -1.992--0.047; p = 0.047) and 12 months after surgery (B, -4.680; 95%CI of B, -8.042--1.319; p = 0.007). Pre-fracture hospitalization was additionally associated with increased mortality rates at 6 months (OR 1.971; 95%CI 1.052-3.693; p = 0.034) and 12 months after surgery (OR 1.888; 95%CI 1.010-9.529; p = 0.046).

CONCLUSIONS

Hip fracture patients with a recent pre-fracture hospital admission are at a substantial risk for inferior functional outcomes and increased mortality rates not only in the perioperative phase but also in the first postoperative year. As a simple dichotomous variable, pre-fracture hospitalization might be a suitable tool for future geriatric hip fracture screening instruments.

摘要

未标注

髋部骨折在老年人中很常见。尽管手术治疗取得了巨大进展,但这些患者的预后仍然令人失望。本研究将骨折前住院确定为围手术期和术后第一年功能预后较差及死亡率增加的一个预后变量。

目的

骨折前住院对髋部骨折患者预后的影响尚未得到研究。

方法

前瞻性纳入402例接受髋部骨折手术治疗的患者。将骨折前3个月内有住院史的患者与无骨折前住院史的患者进行比较。在出院时以及术后6个月和12个月的随访预约时比较两组患者的术后功能预后和死亡率。进行多因素回归分析。

结果

67例患者(17%)报告有骨折前住院史。在63%的病例中,患者因非手术的一般医疗状况入院。在37%的病例中,患者因与手术相关的疾病接受治疗。在多因素分析中,骨折前住院是术后6个月时Barthel指数评分降低(B,-9.918;B的95%置信区间,-19.001--0.835;p = 0.032)以及术后6个月(B,-2.914;B的95%置信区间,-1.992--0.047;p = 0.047)和12个月时Tinetti测试评分降低(B,-4.680;B的95%置信区间,-8.042--1.319;p = 0.007)的独立危险因素。骨折前住院还与术后6个月(OR 1.971;95%置信区间1.052 - 3.693;p = 0.034)和12个月(OR 1.888;95%置信区间1.010 - 9.529;p = 0.046)死亡率增加相关。

结论

近期有骨折前住院史的髋部骨折患者不仅在围手术期,而且在术后第一年都有功能预后较差和死亡率增加的重大风险。作为一个简单的二分变量,骨折前住院可能是未来老年髋部骨折筛查工具的一个合适指标。

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