Hewitt J, Pelisse M, Lessana-Leibowitch M, Sedel D, Fischesser D, Moyal-Barracco M, Frances C, Farcet Y
Rev Stomatol Chir Maxillofac. 1985;86(2):57-65.
The triple association of a chronic painful erosive vulvitis, an erosive or desquamative vaginitis and an erosive vestibular gingivitis constitutes a hitherto unreported syndrome. The first 19 cases of this affection seen in the Hôpital Tarnier over the last three years are presented and analyzed, the etiology of these erosive mucosal lesions, limited to three body regions, being lichen planus in each case. Detection of mucosal erosion at one of these three sites now requires clinical investigation of the other two, and biopsy of least one of them from the edge of an eroded zone, as well as search for other-possible mucocutaneous areas of lichen planus. Clinical onset is often asynchronous, one lesion appearing before the others, the simplest to recognize being gingival erosive lichen. In one case, however, peri-erosive lamellar detachments suggested chronic desquamative gingivitis of possible benign pemphigoid origin. Erosive lichen planus of vulva and vagina has not been reported previously. Knowledge of this syndrome allows correlation between lichen planus and certain cases of erosive gingivitis, erythroplastic vulvitis and desquamative vaginitis.
慢性疼痛性糜烂性外阴炎、糜烂性或脱屑性阴道炎以及糜烂性前庭龈炎三联征构成了一种迄今尚未报道的综合征。本文呈现并分析了过去三年在塔尼尔医院所见的该病症的前19例病例,这些局限于三个身体部位的糜烂性黏膜病变的病因在每例中均为扁平苔藓。现在,在这三个部位之一检测到黏膜糜烂时,需要对另外两个部位进行临床检查,并从糜烂区域边缘至少取其一进行活检,同时还要查找扁平苔藓其他可能的黏膜皮肤区域。临床发病通常不同步,一个病变先于其他病变出现,最容易识别的是牙龈糜烂性扁平苔藓。然而,在一例中,糜烂周围的片状剥离提示可能起源于良性类天疱疮的慢性脱屑性龈炎。此前尚未报道过外阴和阴道的糜烂性扁平苔藓。了解该综合征有助于关联扁平苔藓与某些糜烂性龈炎、增殖性外阴炎及脱屑性阴道炎病例。