Howell L P, Wright A L, Calafati S A, Rosen S, Koprowska I
Acta Cytol. 1985 May-Jun;29(3):269-73.
Three cases of adenocarcinoma of the stomach, two in situ and one superficially invasive, and one of superficially invasive squamous-cell carcinoma of the esophagus are presented to illustrate the problems encountered in the diagnosis of early lesions of the upper gastrointestinal (GI) tract and the contribution that cytodiagnosis can make. The symptomology and roentgenographic findings in these cases were largely nonspecific. While endoscopic biopsies were repeatedly negative in three of the four cases, endoscopic brushing cytology consistently indicated the presence of a malignancy. Surgery was finally performed on the basis of the cytologic findings, confirming the presence of early malignancy. The cytologic findings, with histologic correlations, are presented in an effort to define some specific criteria for the diagnosis of early malignancy of the upper GI tract.
本文报告了3例胃癌，其中2例原位癌，1例浅表浸润癌，以及1例食管浅表浸润性鳞状细胞癌，以说明在上消化道（GI）早期病变诊断中遇到的问题以及细胞诊断所能发挥的作用。这些病例的症状和X线表现大多不具有特异性。在4例中的3例中，内镜活检多次呈阴性，但内镜刷检细胞学检查始终提示存在恶性肿瘤。最终根据细胞学检查结果进行了手术，证实存在早期恶性肿瘤。本文展示了细胞学检查结果并与组织学结果进行了对比，旨在明确一些诊断上消化道早期恶性肿瘤的具体标准。
