Albai Oana, Braha Adina, Timar Bogdan, Golu Ioana, Timar Romulus
Department of Second Internal Medicine-Diabetes, Nutrition, Metabolic Diseases, and Systemic Rheumatology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Department of Diabetes, Nutrition and Metabolic Diseases Clinic, "Pius Brînzeu" Emergency Clinical County University Hospital, 300723 Timisoara, Romania.
J Clin Med. 2024 Feb 28;13(5):1390. doi: 10.3390/jcm13051390.
: Vitamin D is a fat-soluble vitamin that prevents cardiovascular diseases and diabetes mellitus (DM). The present research aimed to study the impact of 25-hydroxyvitamin D (25(OH)D) level on the health status of patients with type 2 DM (T2DM) hospitalized in the "Pius Brînzeu" Emergency Clinical County University Hospital in Timisoara, Romania. : The study retrospectively included 160 patients with T2DM who were clinically and biologically evaluated during hospitalization. : 13.1% of patients had optimal, 23.1% insufficient, and 63.8% deficient 25(OH)D values. Patients with 25(OH)D deficiency presented poorer glycemic control and were older, with higher weight, but had altered renal function, anemia, and lower iron values. Also, patients with associated neoplasia, diabetic neuropathy, cardiovascular disease (CVD), dementia, and grade 3 arterial hypertension (HTN) had lower values of 25(OH)D. An age > 55 years (sensitivity 69.9, specificity 82.5, AUROC 0.786, 0.001) and an HbA1c > 7.7% (sensitivity 89.3, specificity 92.9, AUROC 0.938, 0.001) predict 25(OH)D deficiency in T2DM patients. : Vitamin D influences almost every system and organ in the body, so it should be a routine test for all patients with DM to correct the deficiency and prevent other diseases and complications.
维生素D是一种脂溶性维生素，可预防心血管疾病和糖尿病（DM）。本研究旨在探讨25-羟基维生素D（25(OH)D）水平对罗马尼亚蒂米什瓦拉“皮乌斯·布林泽乌”紧急临床县立大学医院住院的2型糖尿病（T2DM）患者健康状况的影响。
该研究回顾性纳入了160例T2DM患者，这些患者在住院期间进行了临床和生物学评估。
13.1%的患者25(OH)D值处于最佳水平，23.1%不足，63.8%缺乏。25(OH)D缺乏的患者血糖控制较差，年龄较大，体重较高，但肾功能改变、贫血且铁值较低。此外，伴有肿瘤、糖尿病神经病变、心血管疾病（CVD）、痴呆和3级动脉高血压（HTN）的患者25(OH)D值较低。年龄>55岁（敏感性69.9，特异性82.5，曲线下面积0.786，P<0.001）和糖化血红蛋白>7.7%（敏感性89.3，特异性92.9，曲线下面积0.938，P<0.001）可预测T2DM患者的25(OH)D缺乏。
维生素D几乎影响身体的每个系统和器官，因此对所有DM患者进行常规检测以纠正缺乏并预防其他疾病和并发症是必要的。
