Siddiqui Shazia, Manglam Keshav K, Srivastav Anubha, Khan Rehan A, Rastogi Preeti, Shafique Samra
Department of Conservative Dentistry and Endodontics, Career Postgraduate Institute of Dental Sciences and Hospital, Lucknow, India.
Department of Conservative Dentistry and Endodontics, Maharana Pratap Dental College and Hospital, Kanpur, Uttar Pradesh, India.
J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S418-S422. doi: 10.4103/jpbs.jpbs_639_23. Epub 2024 Feb 29.
This study aimed to know the potential of diode light amplification by stimulated emission of radiation (LASER) and desensitizing agents on blocking the dentinal tubules, which may further help in reducing the most common dental problem named dentinal hypersensitivity (DH).
Sixty human permanent bicuspids were selected, and preparation was performed in the cervical region measuring 2.5 mm × 2.5 mm × 2.5 mm, followed by acid etching for 15 seconds. These are then divided according to the groups mentioned: group 1-nano-hydroxyapatite (HA) was applied for 15 minutes; group 2-biosilicate was applied for 15 minutes; group 3-diode LASER application was performed twice for 60 seconds in noncontact mode; group 4-nano-HA plus diode LASER application; and group 5-biosilicate plus diode LASER application. The same procedure was followed on the 1, 7, and 14 days and then rinsed and stored in artificial saliva, and the saliva was changed every 24 hours. The dentinal tubular occlusion was observed under a scanning electron microscope (SEM) after the 14 day.
The maximum dentinal tubular occlusion was observed in group 4, where nano-HA and diode LASER application was performed.
All the investigated treatment groups have promising occluding potential, but the maximum was found in group 4 >group 5 >group 3 >group 1 >group 2. LASER plus desensitizing together prove to be potent and effective in reducing dentinal tubular diameter.
本研究旨在了解二极管受激辐射光放大(激光)和脱敏剂封闭牙本质小管的潜力,这可能有助于进一步减少最常见的牙齿问题——牙本质过敏症(DH)。
选取60颗人类恒牙双尖牙,在颈部区域制备尺寸为2.5mm×2.5mm×2.5mm的样本,随后进行15秒的酸蚀处理。然后根据以下分组:第1组——应用纳米羟基磷灰石(HA)15分钟;第2组——应用生物硅石15分钟;第3组——以非接触模式用二极管激光照射两次,每次60秒;第4组——应用纳米HA并结合二极管激光照射;第5组——应用生物硅石并结合二极管激光照射。在第1、7和14天重复相同步骤,然后冲洗并保存在人工唾液中,每24小时更换一次唾液。14天后在扫描电子显微镜(SEM)下观察牙本质小管的封闭情况。
在第4组(应用纳米HA并结合二极管激光照射)中观察到最大程度的牙本质小管封闭。
所有研究的治疗组都有良好的封闭潜力,但封闭程度最高的是第4组>第5组>第3组>第1组>第2组。激光与脱敏剂联合使用在减小牙本质小管直径方面被证明是有效且高效的。