Paediatric Nephrology Unit, Woman and Children's Hospital, Kuala Lumpur, Malaysia.
Paediatric Nephrology Centre, Hong Kong Children's Hospital, Kowloon, Hong Kong SAR.
Pediatr Nephrol. 2024 Sep;39(9):2641-2643. doi: 10.1007/s00467-024-06364-y. Epub 2024 Apr 10.
Acquired cystic kidney disease (ACKD) can occur in patients with chronic kidney disease and kidney failure, and its incidence increases with the duration of dialysis. In adults, ACKD is less common in the pre-dialysis group (~ 7%), but its incidence can be as high as 80% for those who are on dialysis for more than ten years. There is, however, very little information about the prevalence of ACKD in children. We report a case of malignant transformation of ACKD following a kidney transplant, highlighting the importance of surveillance of the native kidneys in paediatric patients who have been in long-term kidney replacement therapy.
获得性肾囊肿性疾病（ACKD）可发生于慢性肾脏病和肾衰竭患者中，其发病率随透析时间的延长而增加。在成人中，ACKD 在透析前人群中较为少见（~7%），但对于透析时间超过十年的患者，其发病率可高达 80%。然而，关于儿童中 ACKD 的患病率信息却很少。我们报告了一例肾移植后 ACKD 恶变的病例，强调了对长期接受肾脏替代治疗的儿科患者进行对其原有肾脏进行监测的重要性。
