Bozzao L, Antonelli M, Bianco F, Colonnese C, Fantozzi L M, Floris R, Guerrisi V
Riv Neurol. 1985 Mar-Apr;55(2):132-8.
The authors examined by means of computed tomography 12 patients with ALL treated with radiotherapy combined with cytostatic chemotherapy and presenting clinical signs of CNS damage. The CT scan findings are correlated with clinical signs, mainly distinguishing between symptoms of either diffuse or focal damage. An attempt is made in order to evaluate the possible role of Methotrexate and X-Ray therapy in the pathogenesis of the CNS lesions.
作者通过计算机断层扫描检查了12例接受放疗联合细胞抑制化疗且出现中枢神经系统损伤临床症状的急性淋巴细胞白血病患者。CT扫描结果与临床症状相关，主要区分弥漫性或局灶性损伤的症状。旨在评估甲氨蝶呤和X线治疗在中枢神经系统病变发病机制中的可能作用。
