Center for Social and Affective Neuroscience, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Center for Social and Affective Neuroscience, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Immunity. 2024 Apr 9;57(4):837-839. doi: 10.1016/j.immuni.2024.03.011.
Activation of the peripheral immune system contributes to stress-related neuropsychiatric symptoms. Recently in Nature, Cathomas et al. demonstrate that stress-induced social avoidance is mediated by monocyte-derived MMP8 that remodels the extracellular space of the nucleus accumbens.
外周免疫系统的激活有助于与压力相关的神经精神症状。最近在《自然》杂志上,Cathomas 等人表明,应激诱导的社会回避是由单核细胞衍生的 MMP8 介导的,MMP8 重塑了伏隔核的细胞外空间。