Gastroenterology Service, Department of Medicine, Walter Reed National Military Medical Center, Bethesda, Maryland.
Department of Pathology, University of Michigan, Ann Arbor, Michigan.
Ann N Y Acad Sci. 2016 Sep;1380(1):178-182. doi: 10.1111/nyas.13112. Epub 2016 Jul 6.
Sloughing esophagitis, also currently known as esophagitis dissecans superficialis, is a degenerative disease of the squamous epithelium characterized by superficial epithelial necrosis with parakeratosis, but without inflammation, and detachment of the superficial necrotic zone from the deep viable zone. This leads to a spectacular endoscopic appearance of sloughed mucosa in streaks and patches. The cause is unknown, and the clinical characteristics are variable, ranging from incidentally findings to esophageal symptoms. The disease seems to be self-limited, as resolution of the changes was observed in the few cases for which follow-up endoscopic examinations have been reported.
表层性食管融解性炎，亦称食管融解性溃疡，是一种鳞状上皮的退行性疾病，其特征为浅层上皮坏死伴角化不全，但无炎症，以及浅层坏死区与深层存活区分离。这导致了在条纹和斑块中融解的黏膜的壮观内镜外观。病因不明，临床特征多变，从偶然发现到食管症状不等。该疾病似乎是自限性的，因为在为数不多的报道了内镜随访检查的病例中观察到了病变的消退。
