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牙源性黏液瘤的临床谱与治疗:37例分析

Clinical Spectrum and Treatment of Odontogenic Myxoma: Analysis of 37 Cases.

作者信息

Osman Shahd, Hamouda Ghofran M, Eltohami Yousif I

机构信息

Faculty of dentistry, University of Khartoum, Khartoum, Sudan.

Faculty of Dentistry, University of Alneelain, Khartoum, Sudan.

出版信息

J Maxillofac Oral Surg. 2024 Apr;23(2):301-307. doi: 10.1007/s12663-020-01497-7. Epub 2021 Jan 3.

DOI:10.1007/s12663-020-01497-7
PMID:38601247
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11001799/
Abstract

BACKGROUND

Odontogenic myxoma is one of the benign mesenchymal odontogenic tumours with aggressive behaviour and showed slow and asymptomatic expansion, the second until the third decade of life is the most targeted age group. With high female preponderance, about the management, surgical management is the only option concerning this odontogenic pathology with a variety of treatment options. This study aims to analyse a series of 37 patients with odontogenic myxoma treated in a single institution.

MATERIALS AND METHOD

In total, 37 patients with odontogenic myxoma were treated at KTDH in Sudan and were retrospectively reviewed. With the analysis of medical records of all patients diagnosed with odontogenic myxoma and the related variables, data were analysed using the SPSS statistical program (version 23).

RESULTS

Most of the cases were females (26 patients 70.27%), and males were about (11 patients 29.73%). In most of the cases maxilla was affected more than the mandible (25 cases, 67.57%) mostly in its posterior segment (32 cases, 86.49). The most age group affected was the group of cases (0-20) which were about 18 cases (48.65%). In total, 35 of the cases noticed swelling (94.59%), while 14 noticed tooth mobility (37.84%) and paraesthesia was a positive finding in just one case (2.70%). In total, 12 patients (32.43%) had a positive history of tooth extraction related to the lesion, and recurrence was positive in (64, 86%).

CONCLUSION

Odontogenic myxoma is locally aggressive. There is no gold standard protocol for surgical treatment so choosing the most suitable and reliable treatment option relay on the operator taking into consideration the characteristic of each case and the recurrence rate with the associated postoperative impairments.

摘要

背景

牙源性黏液瘤是一种具有侵袭性的良性间叶性牙源性肿瘤,表现为缓慢且无症状的膨胀性生长,第二至第三个十年的生命阶段是最常受累的年龄组。女性患病率高,关于其治疗,手术治疗是针对这种牙源性病变的唯一选择,且有多种治疗方案。本研究旨在分析在单一机构接受治疗的37例牙源性黏液瘤患者。

材料与方法

在苏丹的KTDH共治疗了37例牙源性黏液瘤患者,并进行回顾性分析。通过分析所有诊断为牙源性黏液瘤患者的病历及相关变量,使用SPSS统计程序(版本23)进行数据分析。

结果

大多数病例为女性(26例,70.27%),男性约为(11例,29.73%)。在大多数病例中,上颌比下颌更易受累(25例,67.57%),主要累及后段(32例,86.49%)。受影响最严重的年龄组是(0 - 20岁)组,约18例(48.65%)。总共有35例出现肿胀(94.59%),14例出现牙齿松动(37.84%),仅1例出现感觉异常(2.70%)。总共有12例患者(32.43%)有与病变相关的拔牙史,复发率为(64, 86%)。

结论

牙源性黏液瘤具有局部侵袭性。手术治疗尚无金标准方案,因此选择最合适和可靠的治疗方案取决于操作者,需考虑每个病例的特点以及复发率和相关的术后损伤情况。

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本文引用的文献

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Odontogenic myxoma of the maxilla: A report of a rare case and review on histogenetic and diagnostic concepts.上颌骨牙源性黏液瘤:1例罕见病例报告及组织发生学与诊断概念综述
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Conservative treatment of odontogenic myxoma.牙源性黏液瘤的保守治疗
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Odontogenic myxoma of the maxilla: A report of a rare case and review of the literature.上颌骨牙源性黏液瘤:1例罕见病例报告及文献复习
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Odontogenic myxoma--a case series and review of the surgical management.牙源性黏液瘤——病例系列及手术治疗回顾
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Odontogenic myxoma: a clinicopathologic study of 25 cases.牙源性黏液瘤:25例临床病理研究
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Odontogenic myxoma showing active epithelial islands with microcystic features.牙源性黏液瘤显示具有微囊特征的活跃上皮岛。
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