Teshome Assefa Agegnehu, Walle Ayehu Gashaw, Ashagrie Berhanu Kindu, Baye Nega Dagnaw, Ayenew Atalo Agemas, Mengstie Misganaw Asmamaw, Yazie Taklo Simeneh, Gebeyehu Asaye Alamneh, Sisay Chanie Ermias, Molla Yalew Melkamu, Taye Jemberie Molla, Abate Agmas Wassie
Department of Biomedical Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Pharmacology and Toxicology Unit, Department of Pharmacy, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Front Neurol. 2024 Mar 27;15:1362602. doi: 10.3389/fneur.2024.1362602. eCollection 2024.
The purpose of this systematic review is to answer the focused question, "What is the commonly affected nerve branch and the side of the face involved in trigeminal neuralgia?"
This systematic review included studies reporting commonly affected trigeminal nerve branches and the side of the face involved in trigeminal neuralgia. To find the potential studies published, the authors utilized specific search databases such as PubMed, and Google scholar.
Among 132 published studies, the authors selected only 11 to be included for this systematic review. The sample size ranged from 50 to 43,518 study subjects. This review identified that the mandibular branches of the trigeminal nerve were the most affected, followed by the maxillary branch. The review also identified that the right side of the face was predominantly affected.
The authors of this review identified a higher occurrence of trigeminal neuralgia in the mandibular division of the nerve, commonly affected on the right side of the face. Further prospective-based research and meta-analysis are required to validate the commonly occurring trigeminal nerve branch and sidedness of the face involved with its clinical implications in trigeminal neuralgia.
本系统评价旨在回答聚焦问题，“三叉神经痛中最常受累的神经分支及面部受累侧别是什么？”
本系统评价纳入了报告三叉神经痛中最常受累的神经分支及面部受累侧别的研究。为查找已发表的潜在研究，作者利用了特定的检索数据库，如PubMed和谷歌学术。
在132项已发表的研究中，作者仅选择了11项纳入本系统评价。样本量从50至43,518名研究对象不等。该评价发现，三叉神经的下颌支受累最为常见，其次是上颌支。该评价还发现，面部右侧受累更为普遍。
本评价的作者发现，神经下颌支的三叉神经痛发生率更高，面部右侧通常受累。需要进一步开展基于前瞻性的研究和荟萃分析，以验证三叉神经痛中常见的受累神经分支、面部受累侧别及其临床意义。
