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一名阿拉伯儿科患者中,肠套叠并发未确诊的伯基特淋巴瘤

Intestinal Intussusception Complicating an Undiagnosed Burkitt Lymphoma in a Pediatric Arab Patient.

作者信息

Alghenaim Marwa, Awadh Mohamed, Alshafai Abdulrahman, Darwish Abdulla

机构信息

Department of Pathology and Laboratory Medicine, Bahrain Defense Force (BDF) Royal Medical Services, Riffa, BHR.

Department of Pediatric Surgery, Bahrain Defense Force (BDF) Royal Medical Services, Riffa, BHR.

出版信息

Cureus. 2024 Mar 11;16(3):e55949. doi: 10.7759/cureus.55949. eCollection 2024 Mar.

Abstract

Burkitt's lymphoma (BL) is considered an aggressive form of a non-Hodgkin B-cell lymphoma, representing less than 5% of all pediatric malignancies and 30% of pediatric lymphomas. However, intestinal BL may present as a lead point, causing intussusception. Surgery continues to be the gold standard for the treatment and identification of localized tumors to ensure complete removal with proper margin. In this report, we describe a hidden BL presenting as intestinal intussusception in an eight-year-old Arab boy. A computed tomography (CT) scan of the abdomen revealed an ileoileal intussusception with multiple enlarged lymph nodes. The report discusses the role of histopathology, supported by immunohistochemistry studies, in establishing the diagnosis. It also covers the significance of proper laparoscopic surgery and chemotherapy in the management of this child.

摘要

伯基特淋巴瘤(BL)被认为是一种侵袭性非霍奇金B细胞淋巴瘤,占所有儿童恶性肿瘤的比例不到5%,占儿童淋巴瘤的30%。然而,肠道BL可能表现为套叠的起始点,导致肠套叠。手术仍然是治疗和识别局限性肿瘤的金标准,以确保肿瘤被完整切除且切缘合适。在本报告中,我们描述了一名8岁阿拉伯男孩,其隐匿性BL表现为肠套叠。腹部计算机断层扫描(CT)显示回肠-回肠型肠套叠伴多个肿大淋巴结。本报告讨论了组织病理学在免疫组织化学研究支持下对确诊的作用。它还阐述了合适的腹腔镜手术和化疗在该患儿治疗中的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/11005805/d7d3d6088ad8/cureus-0016-00000055949-i01.jpg

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