School of Nursing, Chengdu Medical College, Chengdu, Sichuan, China.
Department of Nursing, Xuanhan County People's Hospital, Dazhou, Sichuan, China.
Support Care Cancer. 2024 Apr 12;32(5):284. doi: 10.1007/s00520-024-08485-4.
This longitudinal study aims to examine the present state of perceived control, self-management efficacy, and overall quality of life (QoL) in patients with breast cancer undergoing radiotherapy, and gain insight into the dynamic trends and factors that influence the quality of life experienced by patients during the course of radiotherapy.
Participants completed the Cancer Experience and Efficacy Scale (CEES), Strategies Used by People to Promote Health (SUPPH), and Functional Assessment of Cancer Therapy- Breast (FACT-B). The data was analyzed using the software SPSS26.0. Repeated measures analysis of variance (ANOVA) and mixed-effects linear models were used to analyze trends in perceived control, self-management efficacy, and QoL at three-time points, as well as factors affecting QoL during radiotherapy.
Perceived control and self-management efficacy were associated with QoL over the course of the radiotherapy. Self-management efficacy (β = 0.30, P < 0.001), presence of chemotherapy (β = 18.33, P = 0.024), and duration of illness (β = 2.25, P = 0.028) had a positive effect on the change in QoL, while time (β = - 2.95, P < 0.001), cancer experience (β = - 0.46, P < 0.001), and type of medical insurance (β = - 2.77, P = 0.021) had the negative effect on the change in QoL.
The QoL, perceived control, and self-efficacy of patients with breast cancer show dynamic changes during radiotherapy. The higher the self-efficacy, the better the QoL, and the worse the QoL when the sense of disease control is poor. At the same time, more attention should be paid to the QoL of breast cancer radiotherapy patients with a long course of the disease, receiving chemotherapy, and different medical payment methods.
本纵向研究旨在探讨正在接受放疗的乳腺癌患者的感知控制、自我管理效能和总体生活质量（QoL）现状，并深入了解放疗过程中患者生活质量的动态趋势和影响因素。
参与者完成了癌症经历和效能量表（CEES）、促进健康的人们使用的策略（SUPPH）和癌症治疗功能评估-乳房（FACT-B）。使用 SPSS26.0 软件分析数据。使用重复测量方差分析（ANOVA）和混合效应线性模型分析三个时间点感知控制、自我管理效能和 QoL 的趋势，以及放疗期间影响 QoL 的因素。
感知控制和自我管理效能与放疗过程中的 QoL 相关。自我管理效能（β=0.30，P<0.001）、化疗的存在（β=18.33，P=0.024）和疾病持续时间（β=2.25，P=0.028）对 QoL 的变化有积极影响，而时间（β= -2.95，P<0.001）、癌症经历（β= -0.46，P<0.001）和医疗保险类型（β= -2.77，P=0.021）对 QoL 的变化有负面影响。
乳腺癌患者的 QoL、感知控制和自我效能在放疗期间呈现动态变化。自我效能越高，QoL 越好，疾病控制感越差，QoL 越差。同时，应更加关注病程长、接受化疗和不同医疗支付方式的乳腺癌放疗患者的 QoL。
