Mellerup E T, Dam H, Plenge P, Widding A, Rafaelsen O J
Psychiatry Res. 1985 Apr;14(4):309-13. doi: 10.1016/0165-1781(85)90098-8.
Serum lithium was analyzed over a 24-hour period in patients who were receiving lithium in one daily dose. Linear regression was performed with urine volume as the independent variable and lithium dose, maximum serum lithium concentration. 12-hour serum lithium, minimum serum lithium, length of treatment, and age of patients as the dependent variables. Only minimum serum lithium and urine volume showed a good positive correlation.
对每日服用一次锂盐的患者进行了24小时血清锂分析。以尿量为自变量,锂剂量、血清锂最大浓度、12小时血清锂、血清锂最低浓度、治疗时长及患者年龄为因变量进行线性回归分析。仅血清锂最低浓度与尿量呈现良好的正相关。