Okamoto Yoshinori, Wakama Hitoshi, Nakamura Kaito, Ishitani Takashi, Otsuki Shuhei, Neo Masashi
Department of Orthopedic Surgery, Osaka Medical and Pharmaceutical University, Takatsuki, Japan; Department of Orthopedic Surgery, Saiseikai Ibaraki Hospital, Ibaraki, Japan.
Department of Orthopedic Surgery, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.
J Arthroplasty. 2024 Sep;39(9):2303-2310. doi: 10.1016/j.arth.2024.04.016. Epub 2024 Apr 10.
This study aimed to assess the association between the disease process of hip osteoarthritis and total hip arthroplasty (THA) outcomes; this is a critical issue, as rapid progression has been postulated to be responsible for patient dissatisfaction after THA.
This retrospective case-control study included 255 patients who underwent THA and completed a mean follow-up duration of 42.1 months (range, 24.0 to 77.0). We classified patients into those who had (n = 26) and did not have (n = 229) rapidly progressive osteoarthritis of the hip (RPOA), defined as a narrowing rate of joint space ≥ 2 mm yearly or a ≥ 50% loss within 12 months, excluding any other cause of a destructive arthropathy. Propensity score-matched cohorts for age, sex, body mass index, and spino-pelvic measures were created, and the outcomes were compared between the 2 groups.
After successfully matching RPOA (n = 25) and non-RPOA patients (n = 50), there were significant differences in minimum clinically important difference (P = .009 for European Quality of Life 5-Dimension, and P < .001 for low back pain), patient acceptable symptom state (P = .015 for European Quality of Life 5-Dimension, and P < .001 for Hip Disability and Osteoarthritis Outcome Score Joint Replacement score), patient satisfaction (P = .028), and T1 pelvic angle as an indicator of global sagittal spinal deformity (P = .017). There was a correlation between T1 pelvic angle and low back pain in the RPOA group (R = 0.628, P < .001).
Patients who exhibited RPOA before undergoing THA showed worse patient-reported outcomes compared with those who did not have rapid progression. Our study highlights the critical role of the disease process in influencing THA outcomes, advocating for a paradigm shift toward more meticulous preoperative evaluations, including global spinal deformity, standardized diagnostic criteria, and tailored interventions.
本研究旨在评估髋关节骨关节炎的疾病进程与全髋关节置换术(THA)疗效之间的关联;这是一个关键问题,因为快速进展被认为是导致THA术后患者不满意的原因。
这项回顾性病例对照研究纳入了255例行THA且平均随访时间为42.1个月(范围24.0至77.0个月)的患者。我们将患者分为患有(n = 26)和未患有(n = 229)髋关节快速进展性骨关节炎(RPOA)的两组,RPOA定义为关节间隙每年狭窄率≥2 mm或在12个月内丢失≥50%,排除任何其他破坏性关节病的原因。创建了年龄、性别、体重指数和脊柱骨盆测量指标的倾向评分匹配队列,并比较两组的疗效。
成功匹配RPOA患者(n = 25)和非RPOA患者(n = 50)后,最小临床重要差异存在显著差异(欧洲五维生活质量评分为P = 0.009,腰痛评分为P < 0.001)、患者可接受症状状态(欧洲五维生活质量评分为P = 0.015,髋关节残疾和骨关节炎疗效评分关节置换评分为P < 0.001)、患者满意度(P = 0.028)以及作为整体矢状面脊柱畸形指标的T1骨盆角(P = 0.017)。RPOA组中T1骨盆角与腰痛之间存在相关性(R = 0.628,P < 0.001)。
与未出现快速进展的患者相比,在接受THA之前表现出RPOA的患者报告的疗效更差。我们的研究强调了疾病进程在影响THA疗效方面的关键作用,主张向更细致的术前评估模式转变,包括整体脊柱畸形、标准化诊断标准和个性化干预措施。