Shen Yan, Zhang Yi, Fu Jing, Pei Hang, Hua Jiang, He Bangjian
Huzhou Zhengbo Orthopedic Hospital, Huzhou, Zhejiang, China.
Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Front Med (Lausanne). 2025 Aug 14;12:1630171. doi: 10.3389/fmed.2025.1630171. eCollection 2025.
Rapidly destructive hip disease (RDHD) is a rare syndrome marked by swift joint degeneration and substantial functional impairment, typically affecting a single hip joint. The occurrence of bilateral RDHD is exceptionally uncommon, highlighting the urgent need for further research into its pathogenesis, pathological changes, and treatment strategies. We present the case of a 75-year-old female who developed significant bilateral hip mobility limitations and buttock pain 6 months after being diagnosed with mild bilateral hip osteoarthritis. Imaging revealed the disappearance of both femoral heads. After excluding contraindications, the patient successfully underwent left uncemented total hip arthroplasty (THA). Postoperative pathology confirmed the diagnosis, showing degeneration and focal necrosis. This case represents the first documented instance of favorable clinical outcomes following THA in bilateral RDHD.
快速破坏性髋部疾病（RDHD）是一种罕见综合征，其特征为关节迅速退变和严重功能障碍，通常累及单个髋关节。双侧RDHD的发生极为罕见，这凸显了进一步研究其发病机制、病理变化及治疗策略的迫切需求。我们报告一例75岁女性病例，该患者在被诊断为轻度双侧髋关节骨关节炎6个月后，出现双侧髋关节活动严重受限及臀部疼痛。影像学检查显示双侧股骨头消失。排除禁忌证后，患者成功接受了左侧非骨水泥型全髋关节置换术（THA）。术后病理确诊，显示退变和局灶性坏死。该病例是双侧RDHD行THA后取得良好临床疗效的首例有记录病例。
