Department of General Medicine, Saveetha Medical College and Hospital, Thandalam, Chennai, Tamilnadu, India.
Georgian Med News. 2024 Feb(347):59-65.
Ischemic stroke (IS) is a major global health concern, often resulting from atherosclerosis and insulin resistance (IR). The triglyceride-glucose index (TyG index), remnant cholesterol (RC), and common artery intima-media thickness (CIMT) are potential markers for assessing atherosclerosis and cardiovascular risk in IS patients. A cross-sectional study was conducted to investigate the association between TyG index, RC, CIMT, and IS in adult patients recruited from a hospital. Demographic, clinical, and laboratory data were collected, and statistical analysis was performed. The study included 50 participants with a balanced gender distribution and a mean age of 57.64 years. Laboratory characteristics showed notable values, and CIMT > 0.6 mm was associated with higher NIH Stroke Scale scores. RC exhibited significant correlations with age, CIMT, lipid profile, and TyG index. The study highlights the potential of TyG index, RC, and CIMT as atherosclerotic markers in IS patients. Favorable prognostic outcomes were observed, emphasizing the importance of early diagnosis and management to improve patient outcomes.
缺血性脑卒中（IS）是一个全球性的健康问题，常由动脉粥样硬化和胰岛素抵抗（IR）引起。甘油三酯-葡萄糖指数（TyG 指数）、残余胆固醇（RC）和普通动脉内膜中层厚度（CIMT）是评估 IS 患者动脉粥样硬化和心血管风险的潜在标志物。一项横断面研究调查了医院招募的成年 IS 患者的 TyG 指数、RC、CIMT 与 IS 之间的关系。收集了人口统计学、临床和实验室数据，并进行了统计分析。该研究纳入了 50 名性别均衡、平均年龄为 57.64 岁的参与者。实验室特征值显著，CIMT＞0.6mm 与 NIH 卒中量表评分较高相关。RC 与年龄、CIMT、血脂谱和 TyG 指数显著相关。该研究强调了 TyG 指数、RC 和 CIMT 作为 IS 患者动脉粥样硬化标志物的潜力。观察到有利的预后结果，强调早期诊断和管理的重要性，以改善患者结局。
