• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

感染导致的胫骨骨缺损的治疗:单侧髓内钉外固定结合骨搬运技术与环形髓内钉外固定的回顾性对比研究。

Treatment of tibial bone defects caused by infection: a retrospective comparative study of bone transport using a combined technique of unilateral external fixation over an intramedullary nail versus circular external fixation over an intramedullary nail.

机构信息

Department of Trauma and Microreconstructive Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830054, China.

出版信息

BMC Musculoskelet Disord. 2024 Apr 12;25(1):284. doi: 10.1186/s12891-024-07377-2.

DOI:10.1186/s12891-024-07377-2
PMID:38609889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11010327/
Abstract

BACKGROUND

The purpose of the study was to assess and compare the clinical efficacy of bone transport with either circular or unilateral external fixators over an intramedullary nail in the treatment of tibial bone defects caused by infection.

METHODS

Between May 2010 and January 2019, clinical and radiographic data were collected and analyzed for patients with bone defects caused by infection. Thirteen patients underwent bone transport using a unilateral external fixator over an intramedullary nail (Group A), while 12 patients were treated with a circular external fixator over an intramedullary nail (Group B). The bone and functional outcomes of both groups were assessed and compared using the Association for the Study and Application of the Method of the Ilizarov criteria, and postoperative complications were evaluated according to the Paley classification.

RESULTS

A total of 25 patients were successfully treated with bone transport using external fixators over an intramedullary nail, with a mean follow-up time of 31.63 ± 5.88 months. There were no significant statistical differences in age, gender, previous surgery per patient, duration of infection, defect size, and follow-up time between Group A and Group B (P > 0.05). However, statistically significant differences were observed in operation time (187.13 ± 21.88 min vs. 255.76 ± 36.42 min, P = 0.002), intraoperative blood loss (39.26 ± 7.33 mL vs. 53.74 ± 10.69 mL, P < 0.001), external fixation time (2.02 ± 0.31 month vs. 2.57 ± 0.38 month, P = 0.045), external fixation index (0.27 ± 0.08 month/cm vs. 0.44 ± 0.09 month/cm, P = 0.042), and bone union time (8.37 ± 2.30 month vs. 9.07 ± 3.12, P = 0.032) between Group A and Group B. The excellent and good rate of bone and functional results were higher in Group A compared to Group B (76.9% vs. 75% and 84.6% vs. 58.3%). Statistically significant differences were observed in functional results (excellent/good/fair/poor, 5/6/2/0 vs. 2/5/4/1, P = 0.013) and complication per patient (0.38 vs. 1.16, P = 0.012) between Group A and Group B.

CONCLUSIONS

Bone transport using a combined technique of external fixators over an intramedullary nail proved to be an effective method in treating tibial bone defects caused by infection. In comparison to circular external fixators, bone transport utilizing a unilateral external fixator over an intramedullary nail resulted in less external fixation time, fewer complications, and better functional outcomes.

摘要

背景

本研究旨在评估和比较环形或单侧外固定架结合髓内钉骨搬运术治疗感染引起的胫骨骨缺损的临床疗效。

方法

2010 年 5 月至 2019 年 1 月,收集并分析了感染引起骨缺损患者的临床和影像学资料。13 例患者采用单侧外固定架结合髓内钉进行骨搬运(A 组),12 例患者采用环形外固定架结合髓内钉治疗(B 组)。采用伊利扎罗夫方法的应用与研究协会(ASAMI)标准评估两组骨与功能结果,并根据 Paley 分类评估术后并发症。

结果

共 25 例患者成功接受外固定架结合髓内钉骨搬运治疗,平均随访时间为 31.63±5.88 个月。A 组和 B 组在年龄、性别、每位患者的既往手术次数、感染持续时间、缺损大小和随访时间方面无统计学差异(P>0.05)。然而,手术时间(187.13±21.88 min 与 255.76±36.42 min,P=0.002)、术中出血量(39.26±7.33 mL 与 53.74±10.69 mL,P<0.001)、外固定时间(2.02±0.31 月与 2.57±0.38 月,P=0.045)、外固定指数(0.27±0.08 月/cm 与 0.44±0.09 月/cm,P=0.042)和骨愈合时间(8.37±2.30 月与 9.07±3.12 月,P=0.032)有统计学差异。A 组骨与功能结果的优良率高于 B 组(76.9%比 75%和 84.6%比 58.3%)。A 组功能结果(优/良/可/差,5/6/2/0 与 2/5/4/1,P=0.013)和每位患者并发症(0.38 与 1.16,P=0.012)有统计学差异。

结论

髓内钉结合外固定架骨搬运术治疗感染引起的胫骨骨缺损是一种有效的方法。与环形外固定架相比,单侧外固定架结合髓内钉骨搬运术可减少外固定时间,减少并发症,获得更好的功能结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dd9/11010327/69401ad1f09c/12891_2024_7377_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dd9/11010327/cd5c0758549c/12891_2024_7377_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dd9/11010327/69401ad1f09c/12891_2024_7377_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dd9/11010327/cd5c0758549c/12891_2024_7377_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dd9/11010327/69401ad1f09c/12891_2024_7377_Fig2_HTML.jpg

相似文献

1
Treatment of tibial bone defects caused by infection: a retrospective comparative study of bone transport using a combined technique of unilateral external fixation over an intramedullary nail versus circular external fixation over an intramedullary nail.感染导致的胫骨骨缺损的治疗:单侧髓内钉外固定结合骨搬运技术与环形髓内钉外固定的回顾性对比研究。
BMC Musculoskelet Disord. 2024 Apr 12;25(1):284. doi: 10.1186/s12891-024-07377-2.
2
Treatment of tibial large bone defects: A comparative study of bone transport over an intramedullary nail in combination with antibiotic-impregnated calcium sulphate versus bone transport alone with antibiotic-impregnated calcium sulphate.胫骨大骨缺损的治疗:髓内钉联合抗生素浸渍硫酸钙的骨搬运与单纯抗生素浸渍硫酸钙骨搬运的比较研究
Injury. 2023 Apr;54 Suppl 2:S78-S85. doi: 10.1016/j.injury.2022.09.042. Epub 2022 Sep 24.
3
[BONE TRANSPORTATION BY RING TYPE EXTERNAL FIXATOR COMBINED WITH LOCKED INTRAMEDULLARY NAIL FOR TIBIAL NON-INFECTIOUS DEFECT].环形外固定器联合带锁髓内钉治疗胫骨非感染性骨缺损
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2015 Nov;29(11):1348-52.
4
Does Integrated Fixation Provide Benefit in the Reconstruction of Posttraumatic Tibial Bone Defects?综合固定在创伤后胫骨骨缺损重建中是否有益?
Clin Orthop Relat Res. 2015 Oct;473(10):3143-53. doi: 10.1007/s11999-015-4326-6.
5
Ilizarov fixator combined with an intramedullary nail for tibial nonunions with bone loss: is it effective?伊利扎洛夫固定器联合髓内钉治疗伴有骨缺损的胫骨骨不连:有效吗?
Clin Orthop Relat Res. 2014 Dec;472(12):3892-901. doi: 10.1007/s11999-014-3640-8.
6
Complications associated with single-level bone transport for the treatment of tibial bone defects caused by fracture-related infection.与骨折相关感染导致的胫骨骨缺损的单节段骨搬运治疗相关的并发症。
BMC Musculoskelet Disord. 2023 Jun 23;24(1):514. doi: 10.1186/s12891-023-06527-2.
7
Reconstruction of segmental bone defects due to chronic osteomyelitis with use of an external fixator and an intramedullary nail.使用外固定器和髓内钉重建慢性骨髓炎所致节段性骨缺损。
J Bone Joint Surg Am. 2006 Oct;88(10):2137-45. doi: 10.2106/JBJS.E.01152.
8
Efficacy comparison of trifocal bone transport using unilateral external fixator for femoral and tibial bone defects caused by infection.感染导致的股骨和胫骨骨缺损采用单侧外固定器进行三焦点骨搬运的疗效比较。
BMC Surg. 2022 Apr 12;22(1):141. doi: 10.1186/s12893-022-01586-z.
9
Distal tibial reconstruction with use of a circular external fixator and an intramedullary nail. The combined technique.使用环形外固定器和髓内钉进行胫骨远端重建。联合技术。
J Bone Joint Surg Am. 2007 Oct;89(10):2218-24. doi: 10.2106/JBJS.F.01579.
10
Distal tibial reconstruction with use of a circular external fixator and an intramedullary nail. Surgical technique.使用环形外固定器和髓内钉进行胫骨远端重建。手术技术。
J Bone Joint Surg Am. 2008 Oct;90 Suppl 2 Pt 2:181-94. doi: 10.2106/JBJS.H.00467.

引用本文的文献

1
Dual release scaffolds as a promising strategy for enhancing bone regeneration: an updated review.双释放支架作为促进骨再生的一种有前景的策略:最新综述
Nanomedicine (Lond). 2025 Feb;20(4):371-388. doi: 10.1080/17435889.2025.2457317. Epub 2025 Jan 31.
2
Locking compression plate as a sequential external fixator following the distraction phase for the treatment of tibial bone defects caused by fracture-related infection: experiences from 22 cases.锁定加压钢板作为分期外固定器在骨折相关感染所致胫骨骨缺损牵张期后的应用:22例经验
BMC Musculoskelet Disord. 2024 Dec 30;25(1):1088. doi: 10.1186/s12891-024-08221-3.
3

本文引用的文献

1
Efficacy comparison of trifocal bone transport using unilateral external fixator for femoral and tibial bone defects caused by infection.感染导致的股骨和胫骨骨缺损采用单侧外固定器进行三焦点骨搬运的疗效比较。
BMC Surg. 2022 Apr 12;22(1):141. doi: 10.1186/s12893-022-01586-z.
2
Evaluation of complications associated with bifocal bone transport as treatment for either proximal, intermediate or distal femoral defects caused by infection: outcome analysis of 76 patients.评价感染导致的股骨近端、中段或远端骨缺损行双焦骨搬运治疗相关并发症:76 例患者的结局分析。
BMC Musculoskelet Disord. 2022 Feb 9;23(1):132. doi: 10.1186/s12891-022-05078-2.
3
Objective assessment of docking site consolidation in bone transport: the role of pixel value ratio in predicting healing outcomes.
骨搬运中固定部位愈合的客观评估:像素值比值在预测愈合结果中的作用。
J Orthop Surg Res. 2024 Nov 6;19(1):727. doi: 10.1186/s13018-024-05200-1.
Reconstruction of massive tibial defect caused by osteomyelitis using induced membrane followed by trifocal bone transport technique: a retrospective study and our experience.
采用诱导膜技术联合三焦点骨搬运技术治疗骨髓炎导致的胫骨大段骨缺损:回顾性研究及我们的经验。
BMC Surg. 2021 Dec 15;21(1):419. doi: 10.1186/s12893-021-01421-x.
4
Risk factors of pin tract infection during bone transport using unilateral external fixator in the treatment of bone defects.骨搬运过程中使用单侧外固定架治疗骨缺损时针道感染的危险因素。
BMC Surg. 2021 Oct 26;21(1):377. doi: 10.1186/s12893-021-01384-z.
5
Nonunion of the femoral shaft associated with limb shortening treated with a combined technique of external fixation over an intramedullary nail versus the Ilizarov method.股骨干不愈合伴肢体短缩采用髓内钉外固定联合技术与 Ilizarov 方法治疗的比较。
Arch Orthop Trauma Surg. 2022 Sep;142(9):2185-2192. doi: 10.1007/s00402-021-03804-4. Epub 2021 Mar 2.
6
Management of critical-sized bone defects in the treatment of fracture-related infection: a systematic review and pooled analysis.治疗骨折相关感染的临界尺寸骨缺损的管理:系统评价和荟萃分析。
Arch Orthop Trauma Surg. 2021 Jul;141(7):1215-1230. doi: 10.1007/s00402-020-03525-0. Epub 2020 Aug 29.
7
Complications of bone transport technique using the Ilizarov method in the lower extremity: a retrospective analysis of 282 consecutive cases over 10 years.应用 Ilizarov 技术治疗下肢骨搬运术的并发症:10 年 282 例连续病例回顾性分析。
BMC Musculoskelet Disord. 2020 Jun 6;21(1):354. doi: 10.1186/s12891-020-03335-w.
8
Treatment of segmental tibial defects by bone transport with circular external fixation and a locking plate.环形外固定架结合锁定钢板骨搬运治疗胫骨节段性骨缺损。
J Int Med Res. 2020 Apr;48(4):300060520920407. doi: 10.1177/0300060520920407.
9
Intramedullary tibia nailing with external fixation.髓内钉固定联合外固定。
Eur J Trauma Emerg Surg. 2021 Dec;47(6):1947-1955. doi: 10.1007/s00068-020-01351-y. Epub 2020 Mar 27.
10
Efficacy comparison of double-level and single-level bone transport with Orthofix fixator for treatment of tibia fracture with massive bone defects.双层与单层骨搬运联合 Orthofix 固定器治疗胫骨骨折伴大块骨缺损的疗效比较
Int Orthop. 2020 May;44(5):957-963. doi: 10.1007/s00264-020-04503-2. Epub 2020 Feb 29.