Silverman J F, Marrow H G
Acta Cytol. 1985 Jul-Aug;29(4):535-41.
The spectrum of cytomorphologic changes of pulmonary granulomas diagnosed by fine needle aspiration (FNA) biopsy is reported, with a review of the pertinent literature concerning the cytologic diagnosis of granulomatous disease. In our cases, organisms were not seen in the Papanicolaou-stained smears. Recognition of the granulomatous cellular pattern, however, resulted in a thorough search for organisms by special stains, and an etiologic diagnosis was made in each case. These cases emphasize the need for routine staining and culture of FNA material when an initial diagnosis of malignancy is not made. One of the cases appears to be the first report of a nontuberculous Mycobacterium infection diagnosed by fine needle aspiration biopsy.
报告了通过细针穿刺（FNA）活检诊断的肺肉芽肿的细胞形态学变化谱，并回顾了有关肉芽肿性疾病细胞学诊断的相关文献。在我们的病例中，巴氏染色涂片未发现病原体。然而，识别肉芽肿细胞模式后，通过特殊染色对病原体进行了全面搜索，并对每个病例做出了病因诊断。这些病例强调，当初始诊断不是恶性肿瘤时，FNA材料需要进行常规染色和培养。其中一个病例似乎是首例通过细针穿刺活检诊断的非结核分枝杆菌感染报告。
