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连续羊膜腔灌注后早期肾性羊水过少患者的单中心卒中发生率及模式

Single-Center Incidence and Patterns of Stroke in Early Renal Anhydramnios After Serial Amnioinfusions.

作者信息

Lammert Dawn B, Miller Jena L, Atkinson Meredith A, Sun Lisa R

机构信息

Division of Child Neurology, Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD.

Johns Hopkins School of Medicine, Department of Obstetrics and Gynecology, Johns Hopkins Center for Fetal Therapy, Baltimore, MD.

出版信息

J Pediatr. 2024 Aug;271:114053. doi: 10.1016/j.jpeds.2024.114053. Epub 2024 Apr 12.

Abstract

The Renal Anhydramnios Fetal Therapy (RAFT) trial is a study of serial amnioinfusions to prevent lethal neonatal pulmonary hypoplasia from early renal anhydramnios. Infant neurologic outcomes were not originally evaluated. We describe the high incidence of stroke observed among infants in the treatment arm of the trial at our center.

摘要

肾性羊水过少胎儿治疗(RAFT)试验是一项关于连续羊膜腔灌注以预防早期肾性羊水过少所致致命性新生儿肺发育不全的研究。最初并未评估婴儿的神经学结局。我们描述了在我们中心该试验治疗组婴儿中观察到的高卒中发生率。

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